CURENet: Combining Unified Representations for Efficient Chronic Disease Prediction

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to form a comprehensive view of a patient's health, which is crucial for informed therapeutic decision-making. Yet, most predictive models fail to fully capture the interactions, redundancies, and temporal patterns across multiple data modalities, often focusing on a single data type or overlooking these complexities. In this paper, we present CURENet, a multimodal model (Combining Unified Representations for Efficient chronic disease prediction) that integrates unstructured clinical notes, lab tests, and patients' time-series data by utilizing large language models (LLMs) for clinical text processing and textual lab tests, as well as transformer encoders for longitudinal sequential visits. CURENet has been capable of capturing the intricate interaction between different forms of clinical data and creating a more reliable predictive model for chronic illnesses. We evaluated CURENet using the public MIMIC-III and private FEMH datasets, where it achieved over 94\% accuracy in predicting the top 10 chronic conditions in a multi-label framework. Our findings highlight the potential of multimodal EHR integration to enhance clinical decision-making and improve patient outcomes.

EHR-Based Mobile and Web Platform for Chronic Disease Risk Prediction Using Large Language Multimodal Models

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood test values. We collected five years of Electronic Health Records (EHRs) from Taiwan's hospital database between 2017 and 2021 as an AI database. Furthermore, we developed an EHR-based chronic disease prediction platform utilizing Large Language Multimodal Models (LLMMs), successfully integrating with frontend web and mobile applications for prediction. This prediction platform can also connect to the hospital's backend database, providing physicians with real-time risk assessment diagnostics. The demonstration link can be found at https://www.youtube.com/watch?v=oqmL9DEDFgA.