PhyGHT: Physics-Guided HyperGraph Transformer for Signal Purification at the HL-LHC

The High-Luminosity Large Hadron Collider (HL-LHC) at CERN will produce unprecedented datasets capable of revealing fundamental properties of the universe. However, realizing its discovery potential faces a significant challenge: extracting small signal fractions from overwhelming backgrounds dominated by approximately 200 simultaneous pileup collisions. This extreme noise severely distorts the physical observables required for accurate reconstruction. To address this, we introduce the Physics-Guided Hypergraph Transformer (PhyGHT), a hybrid architecture that combines distance-aware local graph attention with global self-attention to mirror the physical topology of particle showers formed in proton-proton collisions. Crucially, we integrate a Pileup Suppression Gate (PSG), an interpretable, physics-constrained mechanism that explicitly learns to filter soft noise prior to hypergraph aggregation. To validate our approach, we release a novel simulated dataset of top-quark pair production to model extreme pileup conditions. PhyGHT outperforms state-of-the-art baselines from the ATLAS and CMS experiments in predicting the signal's energy and mass correction factors. By accurately reconstructing the top quark's invariant mass, we demonstrate how machine learning innovation and interdisciplinary collaboration can directly advance scientific discovery at the frontiers of experimental physics and enhance the HL-LHC's discovery potential. The dataset and code are available at https://github.com/rAIson-Lab/PhyGHT

A Novel Dataset Towards Extracting Virus-Host Interactions

We describe a novel dataset for the automated recognition of named taxonomic and other entities relevant to the association of viruses with their hosts. We further describe some initial results using pre-trained models on the named-entity recognition (NER) task on this novel dataset. We propose that our dataset of manually annotated abstracts now offers a Gold Standard Corpus for training future NER models in the automated extraction of host-pathogen detection methods from scientific publications, and further explain how our work makes first steps towards predicting the important human health-related concept of viral spillover risk automatically from the scientific literature.

Tentacular Artificial Intelligence, and the Architecture Thereof, Introduced

We briefly introduce herein a new form of distributed, multi-agent artificial intelligence, which we refer to as "tentacular." Tentacular AI is distinguished by six attributes, which among other things entail a capacity for reasoning and planning based in highly expressive calculi (logics), and which enlists subsidiary agents across distances circumscribed only by the reach of one or more given networks.