Evolutionary Discovery of Sequence Acceleration Methods for Slab Geometry Neutron Transport

We present a genetic programming approach to automatically discover convergence acceleration methods for discrete ordinates solutions of neutron transport problems in slab geometry. Classical acceleration methods such as Aitken's delta-squared and Wynn epsilon assume specific convergence patterns and do not generalize well to the broad set of transport problems encountered in practice. We evolved mathematical formulas specifically tailored to SN convergence characteristics in this work. The discovered accelerator, featuring second differences and cross-product terms, achieved over 75 percent success rate in improving convergence compared to raw sequences - almost double that observed for classical techniques for the problem set considered. This work demonstrates the potential for discovering novel numerical methods in computational physics via genetic programming and attempts to honor Prof. Ganapol's legacy of advancing experimental mathematics applied to neutron transport.

Automating High Quality RT Planning at Scale

Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances in artificial intelligence (AI) promise to improve its precision, efficiency, and consistency, but progress is often limited by the scarcity of large, standardized datasets. To address this, we introduce the Automated Iterative RT Planning (AIRTP) system, a scalable solution for generating high-quality treatment plans. This scalable solution is designed to generate substantial volumes of consistently high-quality treatment plans, overcoming a key obstacle in the advancement of AI-driven RT planning. Our AIRTP pipeline adheres to clinical guidelines and automates essential steps, including organ-at-risk (OAR) contouring, helper structure creation, beam setup, optimization, and plan quality improvement, using AI integrated with RT planning software like Eclipse of Varian. Furthermore, a novel approach for determining optimization parameters to reproduce 3D dose distributions, i.e. a method to convert dose predictions to deliverable treatment plans constrained by machine limitations. A comparative analysis of plan quality reveals that our automated pipeline produces treatment plans of quality comparable to those generated manually, which traditionally require several hours of labor per plan. Committed to public research, the first data release of our AIRTP pipeline includes nine cohorts covering head-and-neck and lung cancer sites to support an AAPM 2025 challenge. This data set features more than 10 times the number of plans compared to the largest existing well-curated public data set to our best knowledge. Repo:{https://github.com/RiqiangGao/GDP-HMM_AAPMChallenge}