Surrogate-Based Differentiable Pipeline for Shape Optimization

Gradient-based optimization of engineering designs is limited by non-differentiable components in the typical computer-aided engineering (CAE) workflow, which calculates performance metrics from design parameters. While gradient-based methods could provide noticeable speed-ups in high-dimensional design spaces, codes for meshing, physical simulations, and other common components are not differentiable even if the math or physics underneath them is. We propose replacing non-differentiable pipeline components with surrogate models which are inherently differentiable. Using a toy example of aerodynamic shape optimization, we demonstrate an end-to-end differentiable pipeline where a 3D U-Net full-field surrogate replaces both meshing and simulation steps by training it on the mapping between the signed distance field (SDF) of the shape and the fields of interest. This approach enables gradient-based shape optimization without the need for differentiable solvers, which can be useful in situations where adjoint methods are unavailable and/or hard to implement.

MedBench-IT: A Comprehensive Benchmark for Evaluating Large Language Models on Italian Medical Entrance Examinations

Large language models (LLMs) show increasing potential in education, yet benchmarks for non-English languages in specialized domains remain scarce. We introduce MedBench-IT, the first comprehensive benchmark for evaluating LLMs on Italian medical university entrance examinations. Sourced from Edizioni Simone, a leading preparatory materials publisher, MedBench-IT comprises 17,410 expert-written multiple-choice questions across six subjects (Biology, Chemistry, Logic, General Culture, Mathematics, Physics) and three difficulty levels. We evaluated diverse models including proprietary LLMs (GPT-4o, Claude series) and resource-efficient open-source alternatives (<30B parameters) focusing on practical deployability. Beyond accuracy, we conducted rigorous reproducibility tests (88.86% response consistency, varying by subject), ordering bias analysis (minimal impact), and reasoning prompt evaluation. We also examined correlations between question readability and model performance, finding a statistically significant but small inverse relationship. MedBench-IT provides a crucial resource for Italian NLP community, EdTech developers, and practitioners, offering insights into current capabilities and standardized evaluation methodology for this critical domain.