Is Biomedical Specialization Still Worth It? Insights from Domain-Adaptive Language Modelling with a New French Health Corpus

Large language models (LLMs) have demonstrated remarkable capabilities across diverse domains, yet their adaptation to specialized fields remains challenging, particularly for non-English languages. This study investigates domain-adaptive pre-training (DAPT) as a strategy for specializing small to mid-sized LLMs in the French biomedical domain through continued pre-training. We address two key research questions: the viability of specialized continued pre-training for domain adaptation and the relationship between domain-specific performance gains and general capability degradation. Our contributions include the release of a fully open-licensed French biomedical corpus suitable for commercial and open-source applications, the training and release of specialized French biomedical LLMs, and novel insights for DAPT implementation. Our methodology encompasses the collection and refinement of high-quality French biomedical texts, the exploration of causal language modeling approaches using DAPT, and conducting extensive comparative evaluations. Our results cast doubt on the efficacy of DAPT, in contrast to previous works, but we highlight its viability in smaller-scale, resource-constrained scenarios under the right conditions. Findings in this paper further suggest that model merging post-DAPT is essential to mitigate generalization trade-offs, and in some cases even improves performance on specialized tasks at which the DAPT was directed.

Pantagruel: Unified Self-Supervised Encoders for French Text and Speech

We release Pantagruel models, a new family of self-supervised encoder models for French text and speech. Instead of predicting modality-tailored targets such as textual tokens or speech units, Pantagruel learns contextualized target representations in the feature space, allowing modality-specific encoders to capture linguistic and acoustic regularities more effectively. Separate models are pre-trained on large-scale French corpora, including Wikipedia, OSCAR and CroissantLLM for text, together with MultilingualLibriSpeech, LeBenchmark, and INA-100k for speech. INA-100k is a newly introduced 100,000-hour corpus of French audio derived from the archives of the Institut National de l'Audiovisuel (INA), the national repository of French radio and television broadcasts, providing highly diverse audio data. We evaluate Pantagruel across a broad range of downstream tasks spanning both modalities, including those from the standard French benchmarks such as FLUE or LeBenchmark. Across these tasks, Pantagruel models show competitive or superior performance compared to strong French baselines such as CamemBERT, FlauBERT, and LeBenchmark2.0, while maintaining a shared architecture that can seamlessly handle either speech or text inputs. These results confirm the effectiveness of feature-space self-supervised objectives for French representation learning and highlight Pantagruel as a robust foundation for multimodal speech-text understanding.

UMLS-KGI-BERT: Data-Centric Knowledge Integration in Transformers for Biomedical Entity Recognition

Pre-trained transformer language models (LMs) have in recent years become the dominant paradigm in applied NLP. These models have achieved state-of-the-art performance on tasks such as information extraction, question answering, sentiment analysis, document classification and many others. In the biomedical domain, significant progress has been made in adapting this paradigm to NLP tasks that require the integration of domain-specific knowledge as well as statistical modelling of language. In particular, research in this area has focused on the question of how best to construct LMs that take into account not only the patterns of token distribution in medical text, but also the wealth of structured information contained in terminology resources such as the UMLS. This work contributes a data-centric paradigm for enriching the language representations of biomedical transformer-encoder LMs by extracting text sequences from the UMLS. This allows for graph-based learning objectives to be combined with masked-language pre-training. Preliminary results from experiments in the extension of pre-trained LMs as well as training from scratch show that this framework improves downstream performance on multiple biomedical and clinical Named Entity Recognition (NER) tasks.