Automatic Diagnosis of Schizophrenia and Attention Deficit Hyperactivity Disorder in rs-fMRI Modality using Convolutional Autoencoder Model and Interval Type-2 Fuzzy Regression

Nowadays, many people worldwide suffer from brain disorders, and their health is in danger. So far, numerous methods have been proposed for the diagnosis of Schizophrenia (SZ) and attention deficit hyperactivity disorder (ADHD), among which functional magnetic resonance imaging (fMRI) modalities are known as a popular method among physicians. This paper presents an SZ and ADHD intelligent detection method of resting-state fMRI (rs-fMRI) modality using a new deep learning (DL) method. The University of California Los Angeles (UCLA) dataset, which contains the rs-fMRI modalities of SZ and ADHD patients, has been used for experiments. The FMRIB software library (FSL) toolbox first performed preprocessing on rs-fMRI data. Then, a convolutional Autoencoder (CNN-AE) model with the proposed number of layers is used to extract features from rs-fMRI data. In the classification step, a new fuzzy method called interval type-2 fuzzy regression (IT2FR) is introduced and then optimized by genetic algorithm (GA), particle swarm optimization (PSO), and gray wolf optimization (GWO) techniques. Also, the results of IT2FR methods are compared with multilayer perceptron (MLP), k-nearest neighbors (KNN), support vector machine (SVM), random forest (RF), decision tree (DT), and adaptive neuro-fuzzy inference system (ANFIS) methods. The experiment results show that the IT2FR method with the GWO optimization algorithm has achieved satisfactory results compared to other classifier methods. Finally, the proposed classification technique was able to provide 72.71% accuracy.

Controlled Dropout for Uncertainty Estimation

Uncertainty quantification in a neural network is one of the most discussed topics for safety-critical applications. Though Neural Networks (NNs) have achieved state-of-the-art performance for many applications, they still provide unreliable point predictions, which lack information about uncertainty estimates. Among various methods to enable neural networks to estimate uncertainty, Monte Carlo (MC) dropout has gained much popularity in a short period due to its simplicity. In this study, we present a new version of the traditional dropout layer where we are able to fix the number of dropout configurations. As such, each layer can take and apply the new dropout layer in the MC method to quantify the uncertainty associated with NN predictions. We conduct experiments on both toy and realistic datasets and compare the results with the MC method using the traditional dropout layer. Performance analysis utilizing uncertainty evaluation metrics corroborates that our dropout layer offers better performance in most cases.

DoubleU-Net++: Architecture with Exploit Multiscale Features for Vertebrae Segmentation

Accurate segmentation of the vertebra is an important prerequisite in various medical applications (E.g. tele surgery) to assist surgeons. Following the successful development of deep neural networks, recent studies have focused on the essential rule of vertebral segmentation. Prior works contain a large number of parameters, and their segmentation is restricted to only one view. Inspired by DoubleU-Net, we propose a novel model named DoubleU-Net++ in which DensNet as feature extractor, special attention module from Convolutional Block Attention on Module (CBAM) and, Pyramid Squeeze Attention (PSA) module are employed to improve extracted features. We evaluate our proposed model on three different views (sagittal, coronal, and axial) of VerSe2020 and xVertSeg datasets. Compared with state-of-the-art studies, our architecture is trained faster and achieves higher precision, recall, and F1-score as evaluation (imporoved by 4-6%) and the result of above 94% for sagittal view and above 94% for both coronal view and above 93% axial view were gained for VerSe2020 dataset, respectively. Also, for xVertSeg dataset, we achieved precision, recall,and F1-score of above 97% for sagittal view, above 93% for coronal view ,and above 96% for axial view.

Critical Review of Exoskeleton Technology: State of the art and development of physical and cognitive human-robot interface

Exoskeletons and orthoses are wearable mobile systems providing mechanical benefits to the users. Despite significant improvements in the last decades, the technology is not fully mature to be adopted for strenuous and non-programmed tasks. To accommodate this insufficiency, different aspects of this technology need to be analysed and improved. Numerous studies have been trying to address some aspects of exoskeletons, e.g. mechanism design, intent prediction, and control scheme. However, most works have focused on a specific element of design or application without providing a comprehensive review framework. This study aims to analyse and survey the contributing aspects to the improvement and broad adoption of this technology. To address this, after introducing assistive devices and exoskeletons, the main design criteria will be investigated from a physical Human-Robot Interface (HRI) perspective. The study will be further developed by outlining several examples of known assistive devices in different categories. In order to establish an intelligent HRI strategy and enabling intuitive control for users, cognitive HRI will be investigated. Various approaches to this strategy will be reviewed, and a model for intent prediction will be proposed. This model is utilised to predict the gate phase from a single Electromyography (EMG) channel input. The outcomes of modelling show the potential use of single-channel input in low-power assistive devices. Furthermore, the proposed model can provide redundancy in devices with a complex control strategy.

A Comprehensive Study on Torchvision Pre-trained Models for Fine-grained Inter-species Classification

This study aims to explore different pre-trained models offered in the Torchvision package which is available in the PyTorch library. And investigate their effectiveness on fine-grained images classification. Transfer Learning is an effective method of achieving extremely good performance with insufficient training data. In many real-world situations, people cannot collect sufficient data required to train a deep neural network model efficiently. Transfer Learning models are pre-trained on a large data set, and can bring a good performance on smaller datasets with significantly lower training time. Torchvision package offers us many models to apply the Transfer Learning on smaller datasets. Therefore, researchers may need a guideline for the selection of a good model. We investigate Torchvision pre-trained models on four different data sets: 10 Monkey Species, 225 Bird Species, Fruits 360, and Oxford 102 Flowers. These data sets have images of different resolutions, class numbers, and different achievable accuracies. We also apply their usual fully-connected layer and the Spinal fully-connected layer to investigate the effectiveness of SpinalNet. The Spinal fully-connected layer brings better performance in most situations. We apply the same augmentation for different models for the same data set for a fair comparison. This paper may help future Computer Vision researchers in choosing a proper Transfer Learning model.

Improving MC-Dropout Uncertainty Estimates with Calibration Error-based Optimization

Uncertainty quantification of machine learning and deep learning methods plays an important role in enhancing trust to the obtained result. In recent years, a numerous number of uncertainty quantification methods have been introduced. Monte Carlo dropout (MC-Dropout) is one of the most well-known techniques to quantify uncertainty in deep learning methods. In this study, we propose two new loss functions by combining cross entropy with Expected Calibration Error (ECE) and Predictive Entropy (PE). The obtained results clearly show that the new proposed loss functions lead to having a calibrated MC-Dropout method. Our results confirmed the great impact of the new hybrid loss functions for minimising the overlap between the distributions of uncertainty estimates for correct and incorrect predictions without sacrificing the model's overall performance.

Accurate Prediction Using Triangular Type-2 Fuzzy Linear Regression

Many works have been done to handle the uncertainties in the data using type 1 fuzzy regression. Few type 2 fuzzy regression works used interval type 2 for indeterminate modeling using type 1 fuzzy membership. The current survey proposes a triangular type-2 fuzzy regression (TT2FR) model to ameliorate the efficiency of the model by handling the uncertainty in the data. The triangular secondary membership function is used instead of widely used interval type models. In the proposed model, vagueness in primary and secondary fuzzy sets is minimized and also, a specified x-plane of observed value is included in the same {\alpha}- plane of the predicted value. Complex calculations of the type-2 fuzzy (T2F) model are simplified by reducing three dimensional type-2 fuzzy set (3DT2FS) into two dimensional interval type-2 fuzzy (2DIT2F) models. The current survey presents a new regression model of T2F by considering the more general form of T2F membership functions and thus avoids high complexity. The performance of the developed model is evaluated using the TAIEX and COVID-19 forecasting datasets. Our developed model reached the highest performance as compared to the other state-of-art techniques. Our developed method is ready to be tested with more uncertain data and has the potential to use to predict the weather and stock prediction.

Detection of Epileptic Seizures on EEG Signals Using ANFIS Classifier, Autoencoders and Fuzzy Entropies

Epilepsy is one of the most crucial neurological disorders, and its early diagnosis will help the clinicians to provide accurate treatment for the patients. The electroencephalogram (EEG) signals are widely used for epileptic seizures detection, which provides specialists with substantial information about the functioning of the brain. In this paper, a novel diagnostic procedure using fuzzy theory and deep learning techniques are introduced. The proposed method is evaluated on the Bonn University dataset with six classification combinations and also on the Freiburg dataset. The tunable-Q wavelet transform (TQWT) is employed to decompose the EEG signals into different sub-bands. In the feature extraction step, 13 different fuzzy entropies are calculated from different sub-bands of TQWT, and their computational complexities are calculated to help researchers choose the best feature sets. In the following, an autoencoder (AE) with six layers is employed for dimensionality reduction. Finally, the standard adaptive neuro-fuzzy inference system (ANFIS), and also its variants with grasshopper optimization algorithm (ANFIS-GOA), particle swarm optimization (ANFIS-PSO), and breeding swarm optimization (ANFIS-BS) methods are used for classification. Using our proposed method, ANFIS-BS method has obtained an accuracy of 99.74% in classifying into two classes and an accuracy of 99.46% in ternary classification on the Bonn dataset and 99.28% on the Freiburg dataset, reaching state-of-the-art performances on both of them.

MCUa: Multi-level Context and Uncertainty aware Dynamic Deep Ensemble for Breast Cancer Histology Image Classification

Breast histology image classification is a crucial step in the early diagnosis of breast cancer. In breast pathological diagnosis, Convolutional Neural Networks (CNNs) have demonstrated great success using digitized histology slides. However, tissue classification is still challenging due to the high visual variability of the large-sized digitized samples and the lack of contextual information. In this paper, we propose a novel CNN, called Multi-level Context and Uncertainty aware (MCUa) dynamic deep learning ensemble model.MCUamodel consists of several multi-level context-aware models to learn the spatial dependency between image patches in a layer-wise fashion. It exploits the high sensitivity to the multi-level contextual information using an uncertainty quantification component to accomplish a novel dynamic ensemble model.MCUamodelhas achieved a high accuracy of 98.11% on a breast cancer histology image dataset. Experimental results show the superior effectiveness of the proposed solution compared to the state-of-the-art histology classification models.