Advancements in optimization solvers and computing power have led to growing interest in applying whole-body model predictive control (WB-MPC) to bipedal robots. However, the high degrees of freedom and inherent model complexity of bipedal robots pose significant challenges in achieving fast and stable control cycles for real-time performance. This paper introduces a novel kino-dynamic model and warm-start strategy for real-time WB-MPC in bipedal robots. Our proposed kino-dynamic model combines the linear inverted pendulum plus flywheel and full-body kinematics model. Unlike the conventional whole-body model that rely on the concept of contact wrenches, our model utilizes the zero-moment point (ZMP), reducing baseline computational costs and ensuring consistently low latency during contact state transitions. Additionally, a modularized multi-layer perceptron (MLP) based warm-start strategy is proposed, leveraging a lightweight neural network to provide a good initial guess for each control cycle. Furthermore, we present a ZMP-based whole-body controller (WBC) that extends the existing WBC for explicitly controlling impulses and ZMP, integrating it into the real-time WB-MPC framework. Through various comparative experiments, the proposed kino-dynamic model and warm-start strategy have been shown to outperform previous studies. Simulations and real robot experiments further validate that the proposed framework demonstrates robustness to perturbation and satisfies real-time control requirements during walking.