Integrated sensing and communication (ISAC) is a promising candidate technology for 6G due to its improvement in spectral efficiency and energy efficiency. Orthogonal frequency division multiplexing (OFDM) signal is a mainstream candidate ISAC waveform. However, there are inter-symbol interference (ISI) and inter-carrier interference (ICI) when the round-trip delay exceeds the cyclic prefix (CP) duration for OFDM signals, which limits the maximum sensing range of ISAC system. When detecting a long-range target, the wide beam inevitably covers the close-range target, of which the echo's power is much larger than that of the long-range target. In order to tackle the above problem, a multiple signal classification (MUSIC) and least squares (LS)-based spatial signal separation method is proposed to separate the echo signals reflected from different targets. Moreover, a coherent compensation-based sensing signal processing method at the receiver is proposed to enhance the signal to interference plus noise power ratio (SINR) of the OFDM block for generating the range-Doppler map (RDM) with higher SINR. Simulation results reveal that the proposed method greatly enhances the SINR of RDM by 10 dB for a target at 500 m compared with two-dimensional fast Fourier transform (2D-FFT) method. Besides, the detection probability is also significantly improved compared to the benchmarking method.