In recent years, the rapid development of deepfake technology has given rise to an emerging and serious threat to public security: diffusion model-based digital human generation. Unlike traditional face manipulation methods, such models can generate highly realistic videos with consistency through multimodal control signals. Their flexibility and covertness pose severe challenges to existing detection strategies. To bridge this gap, we introduce DigiFakeAV, the first large-scale multimodal digital human forgery dataset based on diffusion models. Employing five latest digital human generation methods (Sonic, Hallo, etc.) and voice cloning method, we systematically produce a dataset comprising 60,000 videos (8.4 million frames), covering multiple nationalities, skin tones, genders, and real-world scenarios, significantly enhancing data diversity and realism. User studies show that the confusion rate between forged and real videos reaches 68%, and existing state-of-the-art (SOTA) detection models exhibit large drops in AUC values on DigiFakeAV, highlighting the challenge of the dataset. To address this problem, we further propose DigiShield, a detection baseline based on spatiotemporal and cross-modal fusion. By jointly modeling the 3D spatiotemporal features of videos and the semantic-acoustic features of audio, DigiShield achieves SOTA performance on both the DigiFakeAV and DF-TIMIT datasets. Experiments show that this method effectively identifies covert artifacts through fine-grained analysis of the temporal evolution of facial features in synthetic videos.