Abstract:Accurate histopathologic interpretation is key for clinical decision-making; however, current deep learning models for digital pathology are often overconfident and poorly calibrated in out-of-distribution (OOD) settings, which limit trust and clinical adoption. Safety-critical medical imaging workflows benefit from intrinsic uncertainty-aware properties that can accurately reject OOD input. We implement the Spectral-normalized Neural Gaussian Process (SNGP), a set of lightweight modifications that apply spectral normalization and replace the final dense layer with a Gaussian process layer to improve single-model uncertainty estimation and OOD detection. We evaluate SNGP vs. deterministic and MonteCarlo dropout on six datasets across three biomedical classification tasks: white blood cells, amyloid plaques, and colorectal histopathology. SNGP has comparable in-distribution performance while significantly improving uncertainty estimation and OOD detection. Thus, SNGP or related models offer a useful framework for uncertainty-aware classification in digital pathology, supporting safe deployment and building trust with pathologists.
Abstract:This research paper addresses the challenge of detecting obscured wildfires (when the fire flames are covered by trees, smoke, clouds, and other natural barriers) in real-time using drones equipped only with RGB cameras. We propose a novel methodology that employs semantic segmentation based on the temporal analysis of smoke patterns in video sequences. Our approach utilizes an encoder-decoder architecture based on deep convolutional neural network architecture with a pre-trained CNN encoder and 3D convolutions for decoding while using sequential stacking of features to exploit temporal variations. The predicted fire locations can assist drones in effectively combating forest fires and pinpoint fire retardant chemical drop on exact flame locations. We applied our method to a curated dataset derived from the FLAME2 dataset that includes RGB video along with IR video to determine the ground truth. Our proposed method has a unique property of detecting obscured fire and achieves a Dice score of 85.88%, while achieving a high precision of 92.47% and classification accuracy of 90.67% on test data showing promising results when inspected visually. Indeed, our method outperforms other methods by a significant margin in terms of video-level fire classification as we obtained about 100% accuracy using MobileNet+CBAM as the encoder backbone.