AI Standardized Patient Improves Human Conversations in Advanced Cancer Care

Serious illness communication (SIC) in end-of-life care faces challenges such as emotional stress, cultural barriers, and balancing hope with honesty. Despite its importance, one of the few available ways for clinicians to practice SIC is with standardized patients, which is expensive, time-consuming, and inflexible. In this paper, we present SOPHIE, an AI-powered standardized patient simulation and automated feedback system. SOPHIE combines large language models (LLMs), a lifelike virtual avatar, and automated, personalized feedback based on clinical literature to provide remote, on-demand SIC training. In a randomized control study with healthcare students and professionals, SOPHIE users demonstrated significant improvement across three critical SIC domains: Empathize, Be Explicit, and Empower. These results suggest that AI-driven tools can enhance complex interpersonal communication skills, offering scalable, accessible solutions to address a critical gap in clinician education.

Reservoir Computing with Noise

This paper investigates in detail the effects of noise on the performance of reservoir computing. We focus on an application in which reservoir computers are used to learn the relationship between different state variables of a chaotic system. We recognize that noise can affect differently the training and testing phases. We find that the best performance of the reservoir is achieved when the strength of the noise that affects the input signal in the training phase equals the strength of the noise that affects the input signal in the testing phase. For all the cases we examined, we found that a good remedy to noise is to low-pass filter the input and the training/testing signals; this typically preserves the performance of the reservoir, while reducing the undesired effects of noise.

Reservoir Computers Modal Decomposition and Optimization

The topology of a network associated with a reservoir computer is often taken so that the connectivity and the weights are chosen randomly. Optimization is hardly considered as the parameter space is typically too large. Here we investigate this problem for a class of reservoir computers for which we obtain a decomposition of the reservoir dynamics into modes, which can be computed independently of one another. Each mode depends on an eigenvalue of the network adjacency matrix. We then take a parametric approach in which the eigenvalues are parameters that can be appropriately designed and optimized. In addition, we introduce the application of a time shift to each individual mode. We show that manipulations of the individual modes, either in terms of the eigenvalues or the time shifts, can lead to dramatic reductions in the training error.