Patient flow analysis can be studied from a clinical and or operational perspective using simulation. Traditional statistical methods such as stochastic distribution methods have been used to construct patient flow simulation submodels such as patient inflow, Length of Stay (LoS), Cost of Treatment (CoT) and Clinical Pathway (CP) models. However, patient inflow demonstrates seasonality, trend and variation over time. LoS, CoT and CP are significantly determined by attributes of patients and clinical and laboratory test results. For this reason, patient flow simulation models constructed using traditional statistical methods are criticized for ignoring heterogeneity and their contribution to personalized and value based healthcare. On the other hand, machine learning methods have proven to be efficient to study and predict admission rate, LoS, CoT, and CP. This paper, hence, describes why coupling machine learning with patient flow simulation is important and proposes a conceptual architecture that shows how to integrate machine learning with patient flow simulation.
This paper presents results of topic modeling and network models of topics using the International Conference on Computational Science corpus, which contains domain-specific (computational science) papers over sixteen years (a total of 5695 papers). We discuss topical structures of International Conference on Computational Science, how these topics evolve over time in response to the topicality of various problems, technologies and methods, and how all these topics relate to one another. This analysis illustrates multidisciplinary research and collaborations among scientific communities, by constructing static and dynamic networks from the topic modeling results and the keywords of authors. The results of this study give insights about the past and future trends of core discussion topics in computational science. We used the Non-negative Matrix Factorization topic modeling algorithm to discover topics and labeled and grouped results hierarchically.