Abstract:Long-term mortality rates after endovascular aneurysm repair (EVAR) remain elevated due to post-EVAR rupture caused by loss of seal in stent graft sealing zones. Structured CT review using centerline measurements improves detection, but current workflows require manual centerline editing and expert operators. We propose a transformer framework for automated, protocol-driven sealing zone assessment that combines 3D centerline tracking with embedding-based geometric prediction. Two state-of-the-art image-to-graph models are evaluated for aorto-iliac centerline extraction from follow-up CT and for measurement of stent position, vessel diameters, and seal lengths according to EVAR4C protocol. Across the full test set and a challenging no-contrast subset, the proposed fully automatic method outperforms the commercial semi-automatic workflow.
Abstract:Sparse vision transformers have gained popularity as efficient encoders for medical volumetric segmentation, with Swin emerging as a prominent choice. Swin uses local attention to reduce complexity and yields excellent performance for many tasks but still tends to overfit on small datasets. To mitigate this weakness, we propose a novel architecture that further enhances Swin's inductive bias by introducing Inception blocks in the feed-forward layers. The introduction of these multi-branch convolutions enables more direct reasoning over local, multi-scale features within the transformer block. We have also modified the decoder layers in order to capture finer details using fewer parameters. We demonstrate a performance improvement on eleven different medical datasets through extensive experimentation. We specifically showcase advancements over the previous state-of-the-art backbones on benchmark challenges like the Medical Segmentation Decathlon and Beyond the Cranial Vault. By showing that the existing inductive bias in Swin can be further improved, our work presents a promising avenue for enhancing the capabilities of sparse vision transformers for both medical and natural image segmentation tasks. Code and pre-trained weights can be accessed at https://github.com/Eiphodos/SwInception.
Abstract:We present ARTA, a mixed-resolution coarse-to-fine vision transformer for efficient dense feature extraction. Unlike models that begin with dense high-resolution (fine) tokens, ARTA starts with low-resolution (coarse) tokens and uses a lightweight allocator to predict which regions require more fine tokens. The allocator iteratively predicts a semantic (class) boundary score and allocates additional tokens to patches above a low threshold, concentrating token density near boundaries while maintaining high sensitivity to weak boundary evidence. This targeted allocation encourages tokens to represent a single semantic class rather than a mixture of classes. Mixed-resolution attention enables interaction between coarse and fine tokens, focusing computation on semantically complex areas while avoiding redundant processing in homogeneous regions. Experiments demonstrate that ARTA achieves state-of-the-art results on ADE20K and COCO-Stuff with substantially fewer FLOPs, and delivers competitive performance on Cityscapes at markedly lower compute. For example, ARTA-Base attains 54.6 mIoU on ADE20K in the ~100M-parameter class while using fewer FLOPs and less memory than comparable backbones.
Abstract:Antibiotic Resistance (AR) is a critical global health challenge that necessitates the development of cost-effective, efficient, and accurate diagnostic tools. Given the genetic basis of AR, techniques such as Polymerase Chain Reaction (PCR) that target specific resistance genes offer a promising approach for predictive diagnostics using a limited set of key genes. This study introduces GenoARM, a novel framework that integrates reinforcement learning (RL) with transformer-based models to optimize the selection of PCR gene tests and improve AR predictions, leveraging observed metadata for improved accuracy. In our evaluation, we developed several high-performing baselines and compared them using publicly available datasets derived from real-world bacterial samples representing multiple clinically relevant pathogens. The results show that all evaluated methods achieve strong and reliable performance when metadata is not utilized. When metadata is introduced and the number of selected genes increases, GenoARM demonstrates superior performance due to its capacity to approximate rewards for unseen and sparse combinations. Overall, our framework represents a major advancement in optimizing diagnostic tools for AR in clinical settings.