From Knowledge to Action: Outcomes of the 2025 Large Language Model (LLM) Hackathon for Applications in Materials Science and Chemistry

Large language models (LLMs) are rapidly changing how researchers in materials science and chemistry discover, organize, and act on scientific knowledge. This paper analyzes a broad set of community-developed LLM applications in an effort to identify emerging patterns in how these systems can be used across the scientific research lifecycle. We organize the projects into two complementary categories: Knowledge Infrastructure, systems that structure, retrieve, synthesize, and validate scientific information; and Action Systems, systems that execute, coordinate, or automate scientific work across computational and experimental environments. The submissions reveal a shift from single-purpose LLM tools toward integrated, multi-agent workflows that combine retrieval, reasoning, tool use, and domain-specific validation. Prominent themes include retrieval-augmented generation as grounding infrastructure, persistent structured knowledge representations, multimodal and multilingual scientific inputs, and early progress toward laboratory-integrated closed-loop systems. Together, these results suggest that LLMs are evolving from general-purpose assistants into composable infrastructure for scientific reasoning and action. This work provides a community snapshot of that transition and a practical taxonomy for understanding emerging LLM-enabled workflows in materials science and chemistry.

A UD Treebank for Bohairic Coptic

Despite recent advances in digital resources for other Coptic dialects, especially Sahidic, Bohairic Coptic, the main Coptic dialect for pre-Mamluk, late Byzantine Egypt, and the contemporary language of the Coptic Church, remains critically under-resourced. This paper presents and evaluates the first syntactically annotated corpus of Bohairic Coptic, sampling data from a range of works, including Biblical text, saints' lives and Christian ascetic writing. We also explore some of the main differences we observe compared to the existing UD treebank of Sahidic Coptic, the classical dialect of the language, and conduct joint and cross-dialect parsing experiments, revealing the unique nature of Bohairic as a related, but distinct variety from the more often studied Sahidic.

Lacuna Language Learning: Leveraging RNNs for Ranked Text Completion in Digitized Coptic Manuscripts

Ancient manuscripts are frequently damaged, containing gaps in the text known as lacunae. In this paper, we present a bidirectional RNN model for character prediction of Coptic characters in manuscript lacunae. Our best model performs with 72% accuracy on single character reconstruction, but falls to 37% when reconstructing lacunae of various lengths. While not suitable for definitive manuscript reconstruction, we argue that our RNN model can help scholars rank the likelihood of textual reconstructions. As evidence, we use our RNN model to rank reconstructions in two early Coptic manuscripts. Our investigation shows that neural models can augment traditional methods of textual restoration, providing scholars with an additional tool to assess lacunae in Coptic manuscripts.