A Classification Benchmark for Artificial Intelligence Detection of Laryngeal Cancer from Patient Speech

Cases of laryngeal cancer are predicted to rise significantly in the coming years. Current diagnostic pathways cause many patients to be incorrectly referred to urgent suspected cancer pathways, putting undue stress on both patients and the medical system. Artificial intelligence offers a promising solution by enabling non-invasive detection of laryngeal cancer from patient speech, which could help prioritise referrals more effectively and reduce inappropriate referrals of non-cancer patients. To realise this potential, open science is crucial. A major barrier in this field is the lack of open-source datasets and reproducible benchmarks, forcing researchers to start from scratch. Our work addresses this challenge by introducing a benchmark suite comprising 36 models trained and evaluated on open-source datasets. These models are accessible in a public repository, providing a foundation for future research. They evaluate three different algorithms and three audio feature sets, offering a comprehensive benchmarking framework. We propose standardised metrics and evaluation methodologies to ensure consistent and comparable results across future studies. The presented models include both audio-only inputs and multimodal inputs that incorporate demographic and symptom data, enabling their application to datasets with diverse patient information. By providing these benchmarks, future researchers can evaluate their datasets, refine the models, and use them as a foundation for more advanced approaches. This work aims to provide a baseline for establishing reproducible benchmarks, enabling researchers to compare new methods against these standards and ultimately advancing the development of AI tools for detecting laryngeal cancer.

Detecting Throat Cancer from Speech Signals Using Machine Learning: A Reproducible Literature Review

In this work we perform a scoping review of the current literature on the detection of throat cancer from speech recordings using machine learning and artificial intelligence. We find 22 papers within this area and discuss their methods and results. We split these papers into two groups - nine performing binary classification, and 13 performing multi-class classification. The papers present a range of methods with neural networks being most commonly implemented. Many features are also extracted from the audio before classification, with the most common bring mel-frequency cepstral coefficients. None of the papers found in this search have associated code repositories and as such are not reproducible. Therefore, we create a publicly available code repository of our own classifiers. We use transfer learning on a multi-class problem, classifying three pathologies and healthy controls. Using this technique we achieve an unweighted average recall of 53.54%, sensitivity of 83.14%, and specificity of 64.00%. We compare our classifiers with the results obtained on the same dataset and find similar results.