MedDChest: A Content-Aware Multimodal Foundational Vision Model for Thoracic Imaging

The performance of vision models in medical imaging is often hindered by the prevailing paradigm of fine-tuning backbones pre-trained on out-of-domain natural images. To address this fundamental domain gap, we propose MedDChest, a new foundational Vision Transformer (ViT) model optimized specifically for thoracic imaging. We pre-trained MedDChest from scratch on a massive, curated, multimodal dataset of over 1.2 million images, encompassing different modalities including Chest X-ray and Computed Tomography (CT) compiled from 10 public sources. A core technical contribution of our work is Guided Random Resized Crops, a novel content-aware data augmentation strategy that biases sampling towards anatomically relevant regions, overcoming the inefficiency of standard cropping techniques on medical scans. We validate our model's effectiveness by fine-tuning it on a diverse set of downstream diagnostic tasks. Comprehensive experiments empirically demonstrate that MedDChest significantly outperforms strong, publicly available ImageNet-pretrained models. By establishing the superiority of large-scale, in-domain pre-training combined with domain-specific data augmentation, MedDChest provides a powerful and robust feature extractor that serves as a significantly better starting point for a wide array of thoracic diagnostic tasks. The model weights will be made publicly available to foster future research and applications.

GNN-MoE: Context-Aware Patch Routing using GNNs for Parameter-Efficient Domain Generalization

Domain generalization (DG) seeks robust Vision Transformer (ViT) performance on unseen domains. Efficiently adapting pretrained ViTs for DG is challenging; standard fine-tuning is costly and can impair generalization. We propose GNN-MoE, enhancing Parameter-Efficient Fine-Tuning (PEFT) for DG with a Mixture-of-Experts (MoE) framework using efficient Kronecker adapters. Instead of token-based routing, a novel Graph Neural Network (GNN) router (GCN, GAT, SAGE) operates on inter-patch graphs to dynamically assign patches to specialized experts. This context-aware GNN routing leverages inter-patch relationships for better adaptation to domain shifts. GNN-MoE achieves state-of-the-art or competitive DG benchmark performance with high parameter efficiency, highlighting the utility of graph-based contextual routing for robust, lightweight DG.