Baseband-Efficient WMMSE Precoding: From a Signal Weighting Cost Perspective

For downlink transmission in massive multi-user multiple-input multiple-output (MU-MIMO) systems, conventional precoding research heavily focuses on reducing the computational complexity of precoding matrix design, while largely overlooking another critical bottleneck: the substantial signal weighting cost incurred by repeatedly applying the precoder to high-speed data streams. To address both challenges simultaneously, this paper proposes a novel sparse precoding framework tailored for fully-digital architectures. Within this framework, from the sum-rate maximization perspective, we design two sparse precoding architectures: a common-support row-sparse architecture and a user-specific row-sparse architecture, so as to reduce the number of multiplication operations required in baseband signal weighting without sacrificing system capacity. For the formulated mixed-integer non-linear programming (MINLP) problem, we rigorously prove, for the first time, that the optimal precoder under both sparse architectures strictly resides in a specific low-dimensional subspace determined by the channel matrices, thereby reducing the dimensionality of the optimization variables. Based on this insight, an alternating optimization algorithm is developed within the weighted minimum mean square error (WMMSE) framework to jointly optimize sparse beam selection and low-dimensional precoding coefficients. The combinatorial beam selection problem is handled using an efficient penalty-based majorize-minimization (MM) method, yielding a low-complexity closed-form solution. Simulation results demonstrate that the proposed scheme achieves near-optimal sum-rate performance while substantially reducing both the precoding computation complexity and the overall signal weighting cost.

Domain-Expert-Guided Hybrid Mixture-of-Experts for Medical AI: Integrating Data-Driven Learning with Clinical Priors

Mixture-of-Experts (MoE) models increase representational capacity with modest computational cost, but their effectiveness in specialized domains such as medicine is limited by small datasets. In contrast, clinical practice offers rich expert knowledge, such as physician gaze patterns and diagnostic heuristics, that models cannot reliably learn from limited data. Combining data-driven experts, which capture novel patterns, with domain-expert-guided experts, which encode accumulated clinical insights, provides complementary strengths for robust and clinically meaningful learning. To this end, we propose Domain-Knowledge-Guided Hybrid MoE (DKGH-MoE), a plug-and-play and interpretable module that unifies data-driven learning with domain expertise. DKGH-MoE integrates a data-driven MoE to extract novel features from raw imaging data, and a domain-expert-guided MoE incorporates clinical priors, specifically clinician eye-gaze cues, to emphasize regions of high diagnostic relevance. By integrating domain expert insights with data-driven features, DKGH-MoE improves both performance and interpretability.