Abstract:Process-based models (PBMs) and deep learning (DL) are two key approaches in agricultural modelling, each offering distinct advantages and limitations. PBMs provide mechanistic insights based on physical and biological principles, ensuring interpretability and scientific rigour. However, they often struggle with scalability, parameterisation, and adaptation to heterogeneous environments. In contrast, DL models excel at capturing complex, nonlinear patterns from large datasets but may suffer from limited interpretability, high computational demands, and overfitting in data-scarce scenarios. This study presents a systematic review of PBMs, DL models, and hybrid PBM-DL frameworks, highlighting their applications in agricultural and environmental modelling. We classify hybrid PBM-DL approaches into DL-informed PBMs, where neural networks refine process-based models, and PBM-informed DL, where physical constraints guide deep learning predictions. Additionally, we conduct a case study on crop dry biomass prediction, comparing hybrid models against standalone PBMs and DL models under varying data quality, sample sizes, and spatial conditions. The results demonstrate that hybrid models consistently outperform traditional PBMs and DL models, offering greater robustness to noisy data and improved generalisation across unseen locations. Finally, we discuss key challenges, including model interpretability, scalability, and data requirements, alongside actionable recommendations for advancing hybrid modelling in agriculture. By integrating domain knowledge with AI-driven approaches, this study contributes to the development of scalable, interpretable, and reproducible agricultural models that support data-driven decision-making for sustainable agriculture.