Visual attention forms the basis of understanding the visual world. In this work we follow a computational approach to investigate the biological basis of visual attention. We analyze retinal and cortical electrophysiological data from mouse. Visual Stimuli are Natural Images depicting real world scenes. Our results show that in primary visual cortex (V1), a subset of around $10\%$ of the neurons responds differently to salient versus non-salient visual regions. Visual attention information was not traced in retinal response. It appears that the retina remains naive concerning visual attention; cortical response gets modulated to interpret visual attention information. Experimental animal studies may be designed to further explore the biological basis of visual attention we traced in this study. In applied and translational science, our study contributes to the design of improved visual prostheses systems -- systems that create artificial visual percepts to visually impaired individuals by electronic implants placed on either the retina or the cortex.
Generative adversarial networks (GANs) are one powerful type of deep learning models that have been successfully utilized in numerous fields. They belong to a broader family called generative methods, which generate new data with a probabilistic model by learning sample distribution from real examples. In the clinical context, GANs have shown enhanced capabilities in capturing spatially complex, nonlinear, and potentially subtle disease effects compared to traditional generative methods. This review appraises the existing literature on the applications of GANs in imaging studies of various neurological conditions, including Alzheimer's disease, brain tumors, brain aging, and multiple sclerosis. We provide an intuitive explanation of various GAN methods for each application and further discuss the main challenges, open questions, and promising future directions of leveraging GANs in neuroimaging. We aim to bridge the gap between advanced deep learning methods and neurology research by highlighting how GANs can be leveraged to support clinical decision making and contribute to a better understanding of the structural and functional patterns of brain diseases.