Abstract:Accurate prognosis prediction is important for treatment planning in lung cancer, but deep learning-driven survival modelling is often limited by the scarcity of curated imaging cohorts with reliable outcome data. This study evaluates whether representations from a domain-specific foundation model can be used for multimodal survival prediction in data-constrained clinical settings. We assess the foundation model CT-CLIP as a feature extractor for pretreatment computed tomography images and clinical variables from 242 diagnosed lung cancer patients. The evaluation includes adaptation strategies based on frozen encoders, full fine-tuning, and low-rank adaptation, together with modality ablations and comparisons with clinical and multimodal baselines. The results show that a frozen CT-CLIP model combined with a trainable lightweight survival head outperforms the clinical baseline and achieves comparable or improved performance relative to other multimodal approaches, and separates patients into clinically meaningful high- and low-risk groups.
Abstract:Deep neural networks (DNNs) are increasingly applied to safety-critical tasks in resource-constrained environments, such as video-based driver action and intention recognition. While last layer probabilistic deep learning (LL-PDL) methods can detect out-of-distribution (OOD) instances, their performance varies. As an alternative to last layer approaches, we propose extending pre-trained DNNs with transformation layers to produce multiple latent representations to estimate the uncertainty. We evaluate our latent uncertainty representation (LUR) and repulsively trained LUR (RLUR) approaches against eight PDL methods across four video-based driver action and intention recognition datasets, comparing classification performance, calibration, and uncertainty-based OOD detection. We also contribute 28,000 frame-level action labels and 1,194 video-level intention labels for the NuScenes dataset. Our results show that LUR and RLUR achieve comparable in-distribution classification performance to other LL-PDL approaches. For uncertainty-based OOD detection, LUR matches top-performing PDL methods while being more efficient to train and easier to tune than approaches that require Markov-Chain Monte Carlo sampling or repulsive training procedures.




Abstract:We envision an integrated process for developing lunar construction equipment, where physical design and control are explored in parallel. In this paper, we describe a technical framework that supports this process. It relies on OpenPLX, a readable/writable declarative language that links CAD-models and autonomous systems to high-fidelity, real-time 3D simulations of contacting multibody dynamics, machine regolith interaction forces, and non-ideal sensors. To demonstrate its capabilities, we present two case studies, including an autonomous lunar rover that combines a vision-language model for navigation with a reinforcement learning-based control policy for locomotion.




Abstract:As vehicle automation technology continues to mature, there is a necessity for robust remote monitoring and intervention features. These are essential for intervening during vehicle malfunctions, challenging road conditions, or in areas that are difficult to navigate. This evolution in the role of the human operator - from a constant driver to an intermittent teleoperator - necessitates the development of suitable interaction interfaces. While some interfaces were suggested, a comparative study is missing. We designed, implemented, and evaluated three interaction concepts (path planning, trajectory guidance, and waypoint guidance) with up to four concurrent requests of automated vehicles in a within-subjects study with N=23 participants. The results showed a clear preference for the path planning concept. It also led to the highest usability but lower satisfaction. With trajectory guidance, the fewest requests were resolved. The study's findings contribute to the ongoing development of HMIs focused on the remote assistance of automated vehicles.