MedOrchestra: A Hybrid Cloud-Local LLM Approach for Clinical Data Interpretation

Deploying large language models (LLMs) in clinical settings faces critical trade-offs: cloud LLMs, with their extensive parameters and superior performance, pose risks to sensitive clinical data privacy, while local LLMs preserve privacy but often fail at complex clinical interpretation tasks. We propose MedOrchestra, a hybrid framework where a cloud LLM decomposes complex clinical tasks into manageable subtasks and prompt generation, while a local LLM executes these subtasks in a privacy-preserving manner. Without accessing clinical data, the cloud LLM generates and validates subtask prompts using clinical guidelines and synthetic test cases. The local LLM executes subtasks locally and synthesizes outputs generated by the cloud LLM. We evaluate MedOrchestra on pancreatic cancer staging using 100 radiology reports under NCCN guidelines. On free-text reports, MedOrchestra achieves 70.21% accuracy, outperforming local model baselines (without guideline: 48.94%, with guideline: 56.59%) and board-certified clinicians (gastroenterologists: 59.57%, surgeons: 65.96%, radiologists: 55.32%). On structured reports, MedOrchestra reaches 85.42% accuracy, showing clear superiority across all settings.

Interactive Visualization for Exploring Information Fragments in Software Repositories

Software developers explore and inspect software repository data to obtain detailed information archived in the development history. However, developers who are not acquainted with the development context suffer from delving into the repositories with a handful of information; they have difficulty discovering and expanding information fragments considering the topological and sequential multi-dimensional structure of repositories. We introduce ExIF, an interactive visualization for exploring information fragments in software repositories. ExIF helps users discover new information fragments within clusters or topological neighbors and identify revisions incorporating user-collected fragments.