Targeted Synthetic Control Method

The synthetic control method (SCM) estimates causal effects in panel data with a single-treated unit by constructing a counterfactual outcome as a weighted combination of untreated control units that matches the pre-treatment trajectory. In this paper, we introduce the targeted synthetic control (TSC) method, a new two-stage estimator that directly estimates the counterfactual outcome. Specifically, our TSC method (1) yields a targeted debiasing estimator, in the sense that the targeted updating refines the initial weights to produce more stable weights; and (2) ensures that the final counterfactual estimation is a convex combination of observed control outcomes to enable direct interpretation of the synthetic control weights. TSC is flexible and can be instantiated with arbitrary machine learning models. Methodologically, TSC starts from an initial set of synthetic-control weights via a one-dimensional targeted update through the weight-tilting submodel, which calibrates the weights to reduce bias of weights estimation arising from pre-treatment fit. Furthermore, TSC avoids key shortcomings of existing methods (e.g., the augmented SCM), which can produce unbounded counterfactual estimates. Across extensive synthetic and real-world experiments, TSC consistently improves estimation accuracy over state-of-the-art SCM baselines.

Rank-Learner: Orthogonal Ranking of Treatment Effects

Many decision-making problems require ranking individuals by their treatment effects rather than estimating the exact effect magnitudes. Examples include prioritizing patients for preventive care interventions, or ranking customers by the expected incremental impact of an advertisement. Surprisingly, while causal effect estimation has received substantial attention in the literature, the problem of directly learning rankings of treatment effects has largely remained unexplored. In this paper, we introduce Rank-Learner, a novel two-stage learner that directly learns the ranking of treatment effects from observational data. We first show that naive approaches based on precise treatment effect estimation solve a harder problem than necessary for ranking, while our Rank-Learner optimizes a pairwise learning objective that recovers the true treatment effect ordering, without explicit CATE estimation. We further show that our Rank-Learner is Neyman-orthogonal and thus comes with strong theoretical guarantees, including robustness to estimation errors in the nuisance functions. In addition, our Rank-Learner is model-agnostic, and can be instantiated with arbitrary machine learning models (e.g., neural networks). We demonstrate the effectiveness of our method through extensive experiments where Rank-Learner consistently outperforms standard CATE estimators and non-orthogonal ranking methods. Overall, we provide practitioners with a new, orthogonal two-stage learner for ranking individuals by their treatment effects.

Foundation Models for Causal Inference via Prior-Data Fitted Networks

Prior-data fitted networks (PFNs) have recently been proposed as a promising way to train tabular foundation models. PFNs are transformers that are pre-trained on synthetic data generated from a prespecified prior distribution and that enable Bayesian inference through in-context learning. In this paper, we introduce CausalFM, a comprehensive framework for training PFN-based foundation models in various causal inference settings. First, we formalize the construction of Bayesian priors for causal inference based on structural causal models (SCMs) in a principled way and derive necessary criteria for the validity of such priors. Building on this, we propose a novel family of prior distributions using causality-inspired Bayesian neural networks that enable CausalFM to perform Bayesian causal inference in various settings, including back-door, front-door, and instrumental variable adjustment. Finally, we instantiate CausalFM and explicitly train a foundation model for estimating conditional average treatment effects (CATEs) using back-door adjustment. We show that CausalFM performs competitively for CATE estimation using various synthetic and semi-synthetic benchmarks. In sum, our framework can be used as a general recipe to train foundation models for various causal inference settings. In contrast to the current state-of-the-art in causal inference, CausalFM offers a novel paradigm with the potential to fundamentally change how practitioners perform causal inference in medicine, economics, and other disciplines.