Reformulating NLP tasks to Capture Longitudinal Manifestation of Language Disorders in People with Dementia

Dementia is associated with language disorders which impede communication. Here, we automatically learn linguistic disorder patterns by making use of a moderately-sized pre-trained language model and forcing it to focus on reformulated natural language processing (NLP) tasks and associated linguistic patterns. Our experiments show that NLP tasks that encapsulate contextual information and enhance the gradient signal with linguistic patterns benefit performance. We then use the probability estimates from the best model to construct digital linguistic markers measuring the overall quality in communication and the intensity of a variety of language disorders. We investigate how the digital markers characterize dementia speech from a longitudinal perspective. We find that our proposed communication marker is able to robustly and reliably characterize the language of people with dementia, outperforming existing linguistic approaches; and shows external validity via significant correlation with clinical markers of behaviour. Finally, our proposed linguistic disorder markers provide useful insights into gradual language impairment associated with disease progression.

A Digital Language Coherence Marker for Monitoring Dementia

The use of spontaneous language to derive appropriate digital markers has become an emergent, promising and non-intrusive method to diagnose and monitor dementia. Here we propose methods to capture language coherence as a cost-effective, human-interpretable digital marker for monitoring cognitive changes in people with dementia. We introduce a novel task to learn the temporal logical consistency of utterances in short transcribed narratives and investigate a range of neural approaches. We compare such language coherence patterns between people with dementia and healthy controls and conduct a longitudinal evaluation against three clinical bio-markers to investigate the reliability of our proposed digital coherence marker. The coherence marker shows a significant difference between people with mild cognitive impairment, those with Alzheimer's Disease and healthy controls. Moreover our analysis shows high association between the coherence marker and the clinical bio-markers as well as generalisability potential to other related conditions.

A Longitudinal Multi-modal Dataset for Dementia Monitoring and Diagnosis

Dementia is a family of neurogenerative conditions affecting memory and cognition in an increasing number of individuals in our globally aging population. Automated analysis of language, speech and paralinguistic indicators have been gaining popularity as potential indicators of cognitive decline. Here we propose a novel longitudinal multi-modal dataset collected from people with mild dementia and age matched controls over a period of several months in a natural setting. The multi-modal data consists of spoken conversations, a subset of which are transcribed, as well as typed and written thoughts and associated extra-linguistic information such as pen strokes and keystrokes. We describe the dataset in detail and proceed to focus on a task using the speech modality. The latter involves distinguishing controls from people with dementia by exploiting the longitudinal nature of the data. Our experiments showed significant differences in how the speech varied from session to session in the control and dementia groups.

Quantum Cognitively Motivated Decision Fusion for Video Sentiment Analysis

Video sentiment analysis as a decision-making process is inherently complex, involving the fusion of decisions from multiple modalities and the so-caused cognitive biases. Inspired by recent advances in quantum cognition, we show that the sentiment judgment from one modality could be incompatible with the judgment from another, i.e., the order matters and they cannot be jointly measured to produce a final decision. Thus the cognitive process exhibits "quantum-like" biases that cannot be captured by classical probability theories. Accordingly, we propose a fundamentally new, quantum cognitively motivated fusion strategy for predicting sentiment judgments. In particular, we formulate utterances as quantum superposition states of positive and negative sentiment judgments, and uni-modal classifiers as mutually incompatible observables, on a complex-valued Hilbert space with positive-operator valued measures. Experiments on two benchmarking datasets illustrate that our model significantly outperforms various existing decision level and a range of state-of-the-art content-level fusion approaches. The results also show that the concept of incompatibility allows effective handling of all combination patterns, including those extreme cases that are wrongly predicted by all uni-modal classifiers.