A Statistical Approach for Modeling Irregular Multivariate Time Series with Missing Observations

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to handle irregularities, we propose a simpler yet effective alternative: extracting time-agnostic summary statistics to eliminate the temporal axis. Our method computes four key features per variable-mean and standard deviation of observed values, as well as the mean and variability of changes between consecutive observations to create a fixed-dimensional representation. These features are then utilized with standard classifiers, such as logistic regression and XGBoost. Evaluated on four biomedical datasets (PhysioNet Challenge 2012, 2019, PAMAP2, and MIMIC-III), our approach achieves state-of-the-art performance, surpassing recent transformer and graph-based models by 0.5-1.7% in AUROC/AUPRC and 1.1-1.7% in accuracy/F1-score, while reducing computational complexity. Ablation studies demonstrate that feature extraction-not classifier choice-drives performance gains, and our summary statistics outperform raw/imputed input in most benchmarks. In particular, we identify scenarios where missing patterns themselves encode predictive signals, as in sepsis prediction (PhysioNet, 2019), where missing indicators alone can achieve 94.2% AUROC with XGBoost, only 1.6% lower than using original raw data as input. Our results challenge the necessity of complex temporal modeling when task objectives permit time-agnostic representations, providing an efficient and interpretable solution for irregular time series classification.

A Green Learning Approach to LDCT Image Restoration

This work proposes a green learning (GL) approach to restore medical images. Without loss of generality, we use low-dose computed tomography (LDCT) images as examples. LDCT images are susceptible to noise and artifacts, where the imaging process introduces distortion. LDCT image restoration is an important preprocessing step for further medical analysis. Deep learning (DL) methods have been developed to solve this problem. We examine an alternative solution using the Green Learning (GL) methodology. The new restoration method is characterized by mathematical transparency, computational and memory efficiency, and high performance. Experiments show that our GL method offers state-of-the-art restoration performance at a smaller model size and with lower inference complexity.

Interpretable and backpropagation-free Green Learning for efficient multi-task echocardiographic segmentation and classification

Echocardiography is a cornerstone for managing heart failure (HF), with Left Ventricular Ejection Fraction (LVEF) being a critical metric for guiding therapy. However, manual LVEF assessment suffers from high inter-observer variability, while existing Deep Learning (DL) models are often computationally intensive and data-hungry "black boxes" that impede clinical trust and adoption. Here, we propose a backpropagation-free multi-task Green Learning (MTGL) framework that performs simultaneous Left Ventricle (LV) segmentation and LVEF classification. Our framework integrates an unsupervised VoxelHop encoder for hierarchical spatio-temporal feature extraction with a multi-level regression decoder and an XG-Boost classifier. On the EchoNet-Dynamic dataset, our MTGL model achieves state-of-the-art classification and segmentation performance, attaining a classification accuracy of 94.3% and a Dice Similarity Coefficient (DSC) of 0.912, significantly outperforming several advanced 3D DL models. Crucially, our model achieves this with over an order of magnitude fewer parameters, demonstrating exceptional computational efficiency. This work demonstrates that the GL paradigm can deliver highly accurate, efficient, and interpretable solutions for complex medical image analysis, paving the way for more sustainable and trustworthy artificial intelligence in clinical practice.

Cross-Modal Fine-Tuning of 3D Convolutional Foundation Models for ADHD Classification with Low-Rank Adaptation

Early diagnosis of attention-deficit/hyperactivity disorder (ADHD) in children plays a crucial role in improving outcomes in education and mental health. Diagnosing ADHD using neuroimaging data, however, remains challenging due to heterogeneous presentations and overlapping symptoms with other conditions. To address this, we propose a novel parameter-efficient transfer learning approach that adapts a large-scale 3D convolutional foundation model, pre-trained on CT images, to an MRI-based ADHD classification task. Our method introduces Low-Rank Adaptation (LoRA) in 3D by factorizing 3D convolutional kernels into 2D low-rank updates, dramatically reducing trainable parameters while achieving superior performance. In a five-fold cross-validated evaluation on a public diffusion MRI database, our 3D LoRA fine-tuning strategy achieved state-of-the-art results, with one model variant reaching 71.9% accuracy and another attaining an AUC of 0.716. Both variants use only 1.64 million trainable parameters (over 113x fewer than a fully fine-tuned foundation model). Our results represent one of the first successful cross-modal (CT-to-MRI) adaptations of a foundation model in neuroimaging, establishing a new benchmark for ADHD classification while greatly improving efficiency.

LG-NuSegHop: A Local-to-Global Self-Supervised Pipeline For Nuclei Instance Segmentation

Nuclei segmentation is the cornerstone task in histology image reading, shedding light on the underlying molecular patterns and leading to disease or cancer diagnosis. Yet, it is a laborious task that requires expertise from trained physicians. The large nuclei variability across different organ tissues and acquisition processes challenges the automation of this task. On the other hand, data annotations are expensive to obtain, and thus, Deep Learning (DL) models are challenged to generalize to unseen organs or different domains. This work proposes Local-to-Global NuSegHop (LG-NuSegHop), a self-supervised pipeline developed on prior knowledge of the problem and molecular biology. There are three distinct modules: (1) a set of local processing operations to generate a pseudolabel, (2) NuSegHop a novel data-driven feature extraction model and (3) a set of global operations to post-process the predictions of NuSegHop. Notably, even though the proposed pipeline uses { no manually annotated training data} or domain adaptation, it maintains a good generalization performance on other datasets. Experiments in three publicly available datasets show that our method outperforms other self-supervised and weakly supervised methods while having a competitive standing among fully supervised methods. Remarkably, every module within LG-NuSegHop is transparent and explainable to physicians.

Deep-JGAC: End-to-End Deep Joint Geometry and Attribute Compression for Dense Colored Point Clouds

Colored point cloud becomes a fundamental representation in the realm of 3D vision. Effective Point Cloud Compression (PCC) is urgently needed due to huge amount of data. In this paper, we propose an end-to-end Deep Joint Geometry and Attribute point cloud Compression (Deep-JGAC) framework for dense colored point clouds, which exploits the correlation between the geometry and attribute for high compression efficiency. Firstly, we propose a flexible Deep-JGAC framework, where the geometry and attribute sub-encoders are compatible to either learning or non-learning based geometry and attribute encoders. Secondly, we propose an attribute-assisted deep geometry encoder that enhances the geometry latent representation with the help of attribute, where the geometry decoding remains unchanged. Moreover, Attribute Information Fusion Module (AIFM) is proposed to fuse attribute information in geometry coding. Thirdly, to solve the mismatch between the point cloud geometry and attribute caused by the geometry compression distortion, we present an optimized re-colorization module to attach the attribute to the geometrically distorted point cloud for attribute coding. It enhances the colorization and lowers the computational complexity. Extensive experimental results demonstrate that in terms of the geometry quality metric D1-PSNR, the proposed Deep-JGAC achieves an average of 82.96%, 36.46%, 41.72%, and 31.16% bit-rate reductions as compared to the state-of-the-art G-PCC, V-PCC, GRASP, and PCGCv2, respectively. In terms of perceptual joint quality metric MS-GraphSIM, the proposed Deep-JGAC achieves an average of 48.72%, 14.67%, and 57.14% bit-rate reductions compared to the G-PCC, V-PCC, and IT-DL-PCC, respectively. The encoding/decoding time costs are also reduced by 94.29%/24.70%, and 96.75%/91.02% on average as compared with the V-PCC and IT-DL-PCC.

Green Video Camouflaged Object Detection

Camouflaged object detection (COD) aims to distinguish hidden objects embedded in an environment highly similar to the object. Conventional video-based COD (VCOD) methods explicitly extract motion cues or employ complex deep learning networks to handle the temporal information, which is limited by high complexity and unstable performance. In this work, we propose a green VCOD method named GreenVCOD. Built upon a green ICOD method, GreenVCOD uses long- and short-term temporal neighborhoods (TN) to capture joint spatial/temporal context information for decision refinement. Experimental results show that GreenVCOD offers competitive performance compared to state-of-the-art VCOD benchmarks.

RadHop-Net: A Lightweight Radiomics-to-Error Regression for False Positive Reduction In MRI Prostate Cancer Detection

Clinically significant prostate cancer (csPCa) is a leading cause of cancer death in men, yet it has a high survival rate if diagnosed early. Bi-parametric MRI (bpMRI) reading has become a prominent screening test for csPCa. However, this process has a high false positive (FP) rate, incurring higher diagnostic costs and patient discomfort. This paper introduces RadHop-Net, a novel and lightweight CNN for FP reduction. The pipeline consists of two stages: Stage 1 employs data driven radiomics to extract candidate ROIs. In contrast, Stage 2 expands the receptive field about each ROI using RadHop-Net to compensate for the predicted error from Stage 1. Moreover, a novel loss function for regression problems is introduced to balance the influence between FPs and true positives (TPs). RadHop-Net is trained in a radiomics-to-error manner, thus decoupling from the common voxel-to-label approach. The proposed Stage 2 improves the average precision (AP) in lesion detection from 0.407 to 0.468 in the publicly available pi-cai dataset, also maintaining a significantly smaller model size than the state-of-the-art.

Efficient Human-Object-Interaction (EHOI) Detection via Interaction Label Coding and Conditional Decision

Human-Object Interaction (HOI) detection is a fundamental task in image understanding. While deep-learning-based HOI methods provide high performance in terms of mean Average Precision (mAP), they are computationally expensive and opaque in training and inference processes. An Efficient HOI (EHOI) detector is proposed in this work to strike a good balance between detection performance, inference complexity, and mathematical transparency. EHOI is a two-stage method. In the first stage, it leverages a frozen object detector to localize the objects and extract various features as intermediate outputs. In the second stage, the first-stage outputs predict the interaction type using the XGBoost classifier. Our contributions include the application of error correction codes (ECCs) to encode rare interaction cases, which reduces the model size and the complexity of the XGBoost classifier in the second stage. Additionally, we provide a mathematical formulation of the relabeling and decision-making process. Apart from the architecture, we present qualitative results to explain the functionalities of the feedforward modules. Experimental results demonstrate the advantages of ECC-coded interaction labels and the excellent balance of detection performance and complexity of the proposed EHOI method.

Word Embedding Dimension Reduction via Weakly-Supervised Feature Selection

As a fundamental task in natural language processing, word embedding converts each word into a representation in a vector space. A challenge with word embedding is that as the vocabulary grows, the vector space's dimension increases and it can lead to a vast model size. Storing and processing word vectors are resource-demanding, especially for mobile edge-devices applications. This paper explores word embedding dimension reduction. To balance computational costs and performance, we propose an efficient and effective weakly-supervised feature selection method, named WordFS. It has two variants, each utilizing novel criteria for feature selection. Experiments conducted on various tasks (e.g., word and sentence similarity and binary and multi-class classification) indicate that the proposed WordFS model outperforms other dimension reduction methods at lower computational costs.