ControlEchoSynth: Boosting Ejection Fraction Estimation Models via Controlled Video Diffusion

Synthetic data generation represents a significant advancement in boosting the performance of machine learning (ML) models, particularly in fields where data acquisition is challenging, such as echocardiography. The acquisition and labeling of echocardiograms (echo) for heart assessment, crucial in point-of-care ultrasound (POCUS) settings, often encounter limitations due to the restricted number of echo views available, typically captured by operators with varying levels of experience. This study proposes a novel approach for enhancing clinical diagnosis accuracy by synthetically generating echo views. These views are conditioned on existing, real views of the heart, focusing specifically on the estimation of ejection fraction (EF), a critical parameter traditionally measured from biplane apical views. By integrating a conditional generative model, we demonstrate an improvement in EF estimation accuracy, providing a comparative analysis with traditional methods. Preliminary results indicate that our synthetic echoes, when used to augment existing datasets, not only enhance EF estimation but also show potential in advancing the development of more robust, accurate, and clinically relevant ML models. This approach is anticipated to catalyze further research in synthetic data applications, paving the way for innovative solutions in medical imaging diagnostics.

BioMamba: Leveraging Spectro-Temporal Embedding in Bidirectional Mamba for Enhanced Biosignal Classification

Biological signals, such as electroencephalograms (EEGs) and electrocardiograms (ECGs), play a pivotal role in numerous clinical practices, such as diagnosing brain and cardiac arrhythmic diseases. Existing methods for biosignal classification rely on Attention-based frameworks with dense Feed Forward layers, which lead to inefficient learning, high computational overhead, and suboptimal performance. In this work, we introduce BioMamba, a Spectro-Temporal Embedding strategy applied to the Bidirectional Mamba framework with Sparse Feed Forward layers to enable effective learning of biosignal sequences. By integrating these three key components, BioMamba effectively addresses the limitations of existing methods. Extensive experiments demonstrate that BioMamba significantly outperforms state-of-the-art methods with marked improvement in classification performance. The advantages of the proposed BioMamba include (1) Reliability: BioMamba consistently delivers robust results, confirmed across six evaluation metrics. (2) Efficiency: We assess both model and training efficiency, the BioMamba demonstrates computational effectiveness by reducing model size and resource consumption compared to existing approaches. (3) Generality: With the capacity to effectively classify a diverse set of tasks, BioMamba demonstrates adaptability and effectiveness across various domains and applications.