Abstract:Large Language Model (LLM) personas with explicit specifications of attributes, background, and behavioural tendencies are increasingly used to simulate human conversations for tasks such as user modeling, social reasoning, and behavioural analysis. Ensuring that persona-grounded simulations faithfully reflect human conversational behaviour is therefore critical. However, current evaluation practices largely rely on LLM-as-a-judge approaches, offering limited grounding in observable human behavior and producing opaque scalar scores. We address this gap by proposing Eval4Sim, an evaluation framework that measures how closely simulated conversations align with human conversational patterns across three complementary dimensions. Adherence captures how effectively persona backgrounds are implicitly encoded in generated utterances, assessed via dense retrieval with speaker-aware representations. Consistency evaluates whether a persona maintains a distinguishable identity across conversations, computed through authorship verification. Naturalness reflects whether conversations exhibit human-like flow rather than overly rigid or optimized structure, quantified through distributions derived from dialogue-focused Natural Language Inference. Unlike absolute or optimization-oriented metrics, Eval4Sim uses a human conversational corpus (i.e., PersonaChat) as a reference baseline and penalizes deviations in both directions, distinguishing insufficient persona encoding from over-optimized, unnatural behaviour. Although demonstrated on PersonaChat, the applicability of Eval4Sim extends to any conversational corpus containing speaker-level annotations.




Abstract:The increasing demand for mental health services has outpaced the availability of real training data to develop clinical professionals, leading to limited support for the diagnosis of depression. This shortage has motivated the development of simulated or virtual patients to assist in training and evaluation, but existing approaches often fail to generate clinically valid, natural, and diverse symptom presentations. In this work, we embrace the recent advanced language models as the backbone and propose a novel clinician-in-the-loop patient simulation pipeline, TalkDep, with access to diversified patient profiles to develop simulated patients. By conditioning the model on psychiatric diagnostic criteria, symptom severity scales, and contextual factors, our goal is to create authentic patient responses that can better support diagnostic model training and evaluation. We verify the reliability of these simulated patients with thorough assessments conducted by clinical professionals. The availability of validated simulated patients offers a scalable and adaptable resource for improving the robustness and generalisability of automatic depression diagnosis systems.