Contrast-Optimized Basis Functions for Self-Navigated Motion Correction in Quantitative MRI

Purpose: The long scan times of quantitative MRI techniques make motion artifacts more likely. For MR-Fingerprinting-like approaches, this problem can be addressed with self-navigated retrospective motion correction based on reconstructions in a singular value decomposition (SVD) subspace. However, the SVD promotes high signal intensity in all tissues, which limits the contrast between tissue types and ultimately reduces the accuracy of registration. The purpose of this paper is to rotate the subspace for maximum contrast between two types of tissue and improve the accuracy of motion estimates. Methods: A subspace is derived that promotes contrasts between brain parenchyma and CSF, achieved through the generalized eigendecomposition of mean autocorrelation matrices, followed by a Gram-Schmidt process to maintain orthogonality. We tested our motion correction method on 85 scans with varying motion levels, acquired with a 3D hybrid-state sequence optimized for quantitative magnetization transfer imaging. Results: A comparative analysis shows that the contrast-optimized basis significantly improve the parenchyma-CSF contrast, leading to smoother motion estimates and reduced artifacts in the quantitative maps. Conclusion: The proposed contrast-optimized subspace improves the accuracy of the motion estimation.

Beyond Automated Evaluation Metrics: Evaluating Topic Models On Practical Social Science Content Analysis Tasks

Topic models are a popular tool for understanding text collections, but their evaluation has been a point of contention. Automated evaluation metrics such as coherence are often used, however, their validity has been questioned for neural topic models (NTMs) and can overlook the benefits of a model in real world applications. To this end, we conduct the first evaluation of neural, supervised and classical topic models in an interactive task based setting. We combine topic models with a classifier and test their ability to help humans conduct content analysis and document annotation. From simulated, real user and expert pilot studies, the Contextual Neural Topic Model does the best on cluster evaluation metrics and human evaluations; however, LDA is competitive with two other NTMs under our simulated experiment and user study results, contrary to what coherence scores suggest. We show that current automated metrics do not provide a complete picture of topic modeling capabilities, but the right choice of NTMs can be better than classical models on practical tasks.

Cheater's Bowl: Human vs. Computer Search Strategies for Open-Domain Question Answering

For humans and computers, the first step in answering an open-domain question is retrieving a set of relevant documents from a large corpus. However, the strategies that computers use fundamentally differ from those of humans. To better understand these differences, we design a gamified interface for data collection -- Cheater's Bowl -- where a human answers complex questions with access to both traditional and modern search tools. We collect a dataset of human search sessions, analyze human search strategies, and compare them to state-of-the-art multi-hop QA models. Humans query logically, apply dynamic search chains, and use world knowledge to boost searching. We demonstrate how human queries can improve the accuracy of existing systems and propose improving the future design of QA models.