ProtoMedAgent: Multimodal Clinical Interpretability via Privacy-Aware Agentic Workflows

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard Retrieval-Augmented Generation (RAG) routinely triggers ``retrieval sycophancy,'' where Large Language Models (LLMs) hallucinate post-hoc rationalizations to align with visual predictions. We introduce ProtoMedAgent, a framework that formalizes multimodal clinical reporting as an iterative, zero-gradient test-time optimization problem over a strict neuro-symbolic bottleneck. Operating on a frozen prototype backbone, we distill latent visual and tabular features into a discrete semantic memory. Online generation is strictly constrained by exact set-theoretic differentials and a reflective Scribe-Critic loop, mathematically precluding unsupported narrative claims. To safely bound data disclosure, we introduce a semantic privacy gate governed by $k$-anonymity and $\ell$-diversity. Evaluated on a 4,160-patient clinical cohort, ProtoMedAgent achieves 91.2\% Comparison Set Faithfulness where it fundamentally outperforms standard RAG (46.2\%). ProtoMedAgent additionally leverages a binding $\ell$-diversity phase transition to systematically reduce artifact-level membership inference risks by an absolute 9.8\%.

ProtoMedX: Towards Explainable Multi-Modal Prototype Learning for Bone Health Classification

Bone health studies are crucial in medical practice for the early detection and treatment of Osteopenia and Osteoporosis. Clinicians usually make a diagnosis based on densitometry (DEXA scans) and patient history. The applications of AI in this field are ongoing research. Most successful methods rely on deep learning models that use vision alone (DEXA/X-ray imagery) and focus on prediction accuracy, while explainability is often disregarded and left to post hoc assessments of input contributions. We propose ProtoMedX, a multi-modal model that uses both DEXA scans of the lumbar spine and patient records. ProtoMedX's prototype-based architecture is explainable by design, which is crucial for medical applications, especially in the context of the upcoming EU AI Act, as it allows explicit analysis of model decisions, including incorrect ones. ProtoMedX demonstrates state-of-the-art performance in bone health classification while also providing explanations that can be visually understood by clinicians. Using a dataset of 4,160 real NHS patients, the proposed ProtoMedX achieves 87.58% accuracy in vision-only tasks and 89.8% in its multi-modal variant, both surpassing existing published methods.

UNICAD: A Unified Approach for Attack Detection, Noise Reduction and Novel Class Identification

As the use of Deep Neural Networks (DNNs) becomes pervasive, their vulnerability to adversarial attacks and limitations in handling unseen classes poses significant challenges. The state-of-the-art offers discrete solutions aimed to tackle individual issues covering specific adversarial attack scenarios, classification or evolving learning. However, real-world systems need to be able to detect and recover from a wide range of adversarial attacks without sacrificing classification accuracy and to flexibly act in {\bf unseen} scenarios. In this paper, UNICAD, is proposed as a novel framework that integrates a variety of techniques to provide an adaptive solution. For the targeted image classification, UNICAD achieves accurate image classification, detects unseen classes, and recovers from adversarial attacks using Prototype and Similarity-based DNNs with denoising autoencoders. Our experiments performed on the CIFAR-10 dataset highlight UNICAD's effectiveness in adversarial mitigation and unseen class classification, outperforming traditional models.

Federated Adversarial Learning for Robust Autonomous Landing Runway Detection

As the development of deep learning techniques in autonomous landing systems continues to grow, one of the major challenges is trust and security in the face of possible adversarial attacks. In this paper, we propose a federated adversarial learning-based framework to detect landing runways using paired data comprising of clean local data and its adversarial version. Firstly, the local model is pre-trained on a large-scale lane detection dataset. Then, instead of exploiting large instance-adaptive models, we resort to a parameter-efficient fine-tuning method known as scale and shift deep features (SSF), upon the pre-trained model. Secondly, in each SSF layer, distributions of clean local data and its adversarial version are disentangled for accurate statistics estimation. To the best of our knowledge, this marks the first instance of federated learning work that address the adversarial sample problem in landing runway detection. Our experimental evaluations over both synthesis and real images of Landing Approach Runway Detection (LARD) dataset consistently demonstrate good performance of the proposed federated adversarial learning and robust to adversarial attacks.