The fast development of Large Language Models (LLMs) offers growing opportunities to further improve sequential recommendation systems. Yet for some practitioners, integrating LLMs to their existing base recommendation systems raises questions about model interpretability, transparency and related safety. To partly alleviate challenges from these questions, we propose guided embedding refinement, a method that carries out a guided and interpretable usage of LLM to enhance the embeddings associated with the base recommendation system. Instead of directly using LLMs as the backbone of sequential recommendation systems, we utilize them as auxiliary tools to emulate the sales logic of recommendation and generate guided embeddings that capture domain-relevant semantic information on interpretable attributes. Benefiting from the strong generalization capabilities of the guided embedding, we construct refined embedding by using the guided embedding and reduced-dimension version of the base embedding. We then integrate the refined embedding into the recommendation module for training and inference. A range of numerical experiments demonstrate that guided embedding is adaptable to various given existing base embedding models, and generalizes well across different recommendation tasks. The numerical results show that the refined embedding not only improves recommendation performance, achieving approximately $10\%$ to $50\%$ gains in Mean Reciprocal Rank (MRR), Recall rate, and Normalized Discounted Cumulative Gain (NDCG), but also enhances interpretability, as evidenced by case studies.