Efficient Mixture-of-Experts LLM Inference with Apple Silicon NPUs

Apple Neural Engine (ANE) is a dedicated neural processing unit (NPU) present in every Apple Silicon chip. Mixture-of-Experts (MoE) LLMs improve inference efficiency via sparse activation but are challenging for NPUs in three ways: expert routing is unpredictable and introduces dynamic tensor shapes that conflict with the shape-specific constraints of NPUs; several irregular operators, e.g., top-k, scatter/gather, etc., are not NPU-friendly; and launching many small expert kernels incurs substantial dispatch and synchronization overhead. NPUs are designed to offload AI compute from CPU and GPU; our goal is to enable such offloading for MoE inference, particularly during prefill, where long-context workloads consume substantial system resources. This paper presents NPUMoE, a runtime inference engine that accelerates MoE execution on Apple Silicon by offloading dense, static computation to NPU, while preserving a CPU/GPU fallback path for dynamic operations. NPUMoE uses offline calibration to estimate expert capacity and popularity that drives three key techniques: (1) Static tiers for expert capacity to address dynamic expert routing (2) Grouped expert execution to mitigate NPU concurrency limits (3) Load-aware expert compute graph residency to reduce CPU-NPU synchronization overhead. Experiments on Apple M-series devices using three representative MoE LLMs and four long-context workloads show that NPUMoE consistently outperforms baselines, reducing latency by 1.32x-5.55x, improving energy efficiency by 1.81x-7.37x, and reducing CPU-cycle usage by 1.78x-5.54x through effective NPU offloading.