Catching the Infection Before It Spreads: Foresight-Guided Defense in Multi-Agent Systems

Large multimodal model-based Multi-Agent Systems (MASs) enable collaborative complex problem solving through specialized agents. However, MASs are vulnerable to infectious jailbreak, where compromising a single agent can spread to others, leading to widespread compromise. Existing defenses counter this by training a more contagious cure factor, biasing agents to retrieve it over virus adversarial examples (VirAEs). However, this homogenizes agent responses, providing only superficial suppression rather than true recovery. We revisit these defenses, which operate globally via a shared cure factor, while infectious jailbreak arise from localized interaction behaviors. This mismatch limits their effectiveness. To address this, we propose a training-free Foresight-Guided Local Purification (FLP) framework, where each agent reasons over future interactions to track behavioral evolution and eliminate infections. Specifically, each agent simulates future behavioral trajectories over subsequent chat rounds. To reflect diversity in MASs, we introduce a multi-persona simulation strategy for robust prediction across interaction contexts. We then use response diversity as a diagnostic signal to detect infection by analyzing inconsistencies across persona-based predictions at both retrieval-result and semantic levels. For infected agents, we apply localized purification: recent infections are mitigated via immediate album rollback, while long-term infections are handled using Recursive Binary Diagnosis (RBD), which recursively partitions the image album and applies the same diagnosis strategy to localize and eliminate VirAEs. Experiments show that FLP reduces the maximum cumulative infection rate from over 95% to below 5.47%. Moreover, retrieval and semantic metrics closely match benign baselines, indicating effective preservation of interaction diversity.