Antithetic Noise in Diffusion Models

We initiate a systematic study of antithetic initial noise in diffusion models. Across unconditional models trained on diverse datasets, text-conditioned latent-diffusion models, and diffusion-posterior samplers, we find that pairing each initial noise with its negation consistently yields strongly negatively correlated samples. To explain this phenomenon, we combine experiments and theoretical analysis, leading to a symmetry conjecture that the learned score function is approximately affine antisymmetric (odd symmetry up to a constant shift), and provide evidence supporting it. Leveraging this negative correlation, we enable two applications: (1) enhancing image diversity in models like Stable Diffusion without quality loss, and (2) sharpening uncertainty quantification (e.g., up to 90% narrower confidence intervals) when estimating downstream statistics. Building on these gains, we extend the two-point pairing to a randomized quasi-Monte Carlo estimator, which further improves estimation accuracy. Our framework is training-free, model-agnostic, and adds no runtime overhead.