Pushing Boundaries: Exploring Zero Shot Object Classification with Large Multimodal Models

$ $The synergy of language and vision models has given rise to Large Language and Vision Assistant models (LLVAs), designed to engage users in rich conversational experiences intertwined with image-based queries. These comprehensive multimodal models seamlessly integrate vision encoders with Large Language Models (LLMs), expanding their applications in general-purpose language and visual comprehension. The advent of Large Multimodal Models (LMMs) heralds a new era in Artificial Intelligence (AI) assistance, extending the horizons of AI utilization. This paper takes a unique perspective on LMMs, exploring their efficacy in performing image classification tasks using tailored prompts designed for specific datasets. We also investigate the LLVAs zero-shot learning capabilities. Our study includes a benchmarking analysis across four diverse datasets: MNIST, Cats Vs. Dogs, Hymnoptera (Ants Vs. Bees), and an unconventional dataset comprising Pox Vs. Non-Pox skin images. The results of our experiments demonstrate the model's remarkable performance, achieving classification accuracies of 85\%, 100\%, 77\%, and 79\% for the respective datasets without any fine-tuning. To bolster our analysis, we assess the model's performance post fine-tuning for specific tasks. In one instance, fine-tuning is conducted over a dataset comprising images of faces of children with and without autism. Prior to fine-tuning, the model demonstrated a test accuracy of 55\%, which significantly improved to 83\% post fine-tuning. These results, coupled with our prior findings, underscore the transformative potential of LLVAs and their versatile applications in real-world scenarios.

Can ChatGPT be Your Personal Medical Assistant?

The advanced large language model (LLM) ChatGPT has shown its potential in different domains and remains unbeaten due to its characteristics compared to other LLMs. This study aims to evaluate the potential of using a fine-tuned ChatGPT model as a personal medical assistant in the Arabic language. To do so, this study uses publicly available online questions and answering datasets in Arabic language. There are almost 430K questions and answers for 20 disease-specific categories. GPT-3.5-turbo model was fine-tuned with a portion of this dataset. The performance of this fine-tuned model was evaluated through automated and human evaluation. The automated evaluations include perplexity, coherence, similarity, and token count. Native Arabic speakers with medical knowledge evaluated the generated text by calculating relevance, accuracy, precision, logic, and originality. The overall result shows that ChatGPT has a bright future in medical assistance.

Improving diagnosis and prognosis of lung cancer using vision transformers: A scoping review

Vision transformer-based methods are advancing the field of medical artificial intelligence and cancer imaging, including lung cancer applications. Recently, many researchers have developed vision transformer-based AI methods for lung cancer diagnosis and prognosis. This scoping review aims to identify the recent developments on vision transformer-based AI methods for lung cancer imaging applications. It provides key insights into how vision transformers complemented the performance of AI and deep learning methods for lung cancer. Furthermore, the review also identifies the datasets that contributed to advancing the field. Of the 314 retrieved studies, this review included 34 studies published from 2020 to 2022. The most commonly addressed task in these studies was the classification of lung cancer types, such as lung squamous cell carcinoma versus lung adenocarcinoma, and identifying benign versus malignant pulmonary nodules. Other applications included survival prediction of lung cancer patients and segmentation of lungs. The studies lacked clear strategies for clinical transformation. SWIN transformer was a popular choice of the researchers; however, many other architectures were also reported where vision transformer was combined with convolutional neural networks or UNet model. It can be concluded that vision transformer-based models are increasingly in popularity for developing AI methods for lung cancer applications. However, their computational complexity and clinical relevance are important factors to be considered for future research work. This review provides valuable insights for researchers in the field of AI and healthcare to advance the state-of-the-art in lung cancer diagnosis and prognosis. We provide an interactive dashboard on lung-cancer.onrender.com/.

Artificial Intelligence-Based Methods for Precision Medicine: Diabetes Risk Prediction

The rising prevalence of type 2 diabetes mellitus (T2DM) necessitates the development of predictive models for T2DM risk assessment. Artificial intelligence (AI) models are being extensively used for this purpose, but a comprehensive review of their advancements and challenges is lacking. This scoping review analyzes existing literature on AI-based models for T2DM risk prediction. Forty studies were included, mainly published in the past four years. Traditional machine learning models were more prevalent than deep learning models. Electronic health records were the most commonly used data source. Unimodal AI models relying on EHR data were prominent, while only a few utilized multimodal models. Both unimodal and multimodal models showed promising performance, with the latter outperforming the former. Internal validation was common, while external validation was limited. Interpretability methods were reported in half of the studies. Few studies reported novel biomarkers, and open-source code availability was limited. This review provides insights into the current state and limitations of AI-based T2DM risk prediction models and highlights challenges for their development and clinical implementation.

Leveraging GANs for data scarcity of COVID-19: Beyond the hype

Artificial Intelligence (AI)-based models can help in diagnosing COVID-19 from lung CT scans and X-ray images; however, these models require large amounts of data for training and validation. Many researchers studied Generative Adversarial Networks (GANs) for producing synthetic lung CT scans and X-Ray images to improve the performance of AI-based models. It is not well explored how good GAN-based methods performed to generate reliable synthetic data. This work analyzes 43 published studies that reported GANs for synthetic data generation. Many of these studies suffered data bias, lack of reproducibility, and lack of feedback from the radiologists or other domain experts. A common issue in these studies is the unavailability of the source code, hindering reproducibility. The included studies reported rescaling of the input images to train the existing GANs architecture without providing clinical insights on how the rescaling was motivated. Finally, even though GAN-based methods have the potential for data augmentation and improving the training of AI-based models, these methods fall short in terms of their use in clinical practice. This paper highlights research hotspots in countering the data scarcity problem, identifies various issues as well as potentials, and provides recommendations to guide future research. These recommendations might be useful to improve acceptability for the GAN-based approaches for data augmentation as GANs for data augmentation are increasingly becoming popular in the AI and medical imaging research community.

Brain Tumor Synthetic Data Generation with Adaptive StyleGANs

Generative models have been very successful over the years and have received significant attention for synthetic data generation. As deep learning models are getting more and more complex, they require large amounts of data to perform accurately. In medical image analysis, such generative models play a crucial role as the available data is limited due to challenges related to data privacy, lack of data diversity, or uneven data distributions. In this paper, we present a method to generate brain tumor MRI images using generative adversarial networks. We have utilized StyleGAN2 with ADA methodology to generate high-quality brain MRI with tumors while using a significantly smaller amount of training data when compared to the existing approaches. We use three pre-trained models for transfer learning. Results demonstrate that the proposed method can learn the distributions of brain tumors. Furthermore, the model can generate high-quality synthetic brain MRI with a tumor that can limit the small sample size issues. The approach can addresses the limited data availability by generating realistic-looking brain MRI with tumors. The code is available at: ~\url{https://github.com/rizwanqureshi123/Brain-Tumor-Synthetic-Data}.

Spot the fake lungs: Generating Synthetic Medical Images using Neural Diffusion Models

Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images is not explored yet. In this work, we explore the possibilities of synthesis of medical images using neural diffusion models. First, we use a pre-trained DALLE2 model to generate lungs X-Ray and CT images from an input text prompt. Second, we train a stable diffusion model with 3165 X-Ray images and generate synthetic images. We evaluate the synthetic image data through a qualitative analysis where two independent radiologists label randomly chosen samples from the generated data as real, fake, or unsure. Results demonstrate that images generated with the diffusion model can translate characteristics that are otherwise very specific to certain medical conditions in chest X-Ray or CT images. Careful tuning of the model can be very promising. To the best of our knowledge, this is the first attempt to generate lungs X-Ray and CT images using neural diffusion models. This work aims to introduce a new dimension in artificial intelligence for medical imaging. Given that this is a new topic, the paper will serve as an introduction and motivation for the research community to explore the potential of diffusion models for medical image synthesis. We have released the synthetic images on https://www.kaggle.com/datasets/hazrat/awesomelungs.

Artificial Intelligence-Based Methods for Fusion of Electronic Health Records and Imaging Data

Healthcare data are inherently multimodal, including electronic health records (EHR), medical images, and multi-omics data. Combining these multimodal data sources contributes to a better understanding of human health and provides optimal personalized healthcare. Advances in artificial intelligence (AI) technologies, particularly machine learning (ML), enable the fusion of these different data modalities to provide multimodal insights. To this end, in this scoping review, we focus on synthesizing and analyzing the literature that uses AI techniques to fuse multimodal medical data for different clinical applications. More specifically, we focus on studies that only fused EHR with medical imaging data to develop various AI methods for clinical applications. We present a comprehensive analysis of the various fusion strategies, the diseases and clinical outcomes for which multimodal fusion was used, the ML algorithms used to perform multimodal fusion for each clinical application, and the available multimodal medical datasets. We followed the PRISMA-ScR guidelines. We searched Embase, PubMed, Scopus, and Google Scholar to retrieve relevant studies. We extracted data from 34 studies that fulfilled the inclusion criteria. In our analysis, a typical workflow was observed: feeding raw data, fusing different data modalities by applying conventional machine learning (ML) or deep learning (DL) algorithms, and finally, evaluating the multimodal fusion through clinical outcome predictions. Specifically, early fusion was the most used technique in most applications for multimodal learning (22 out of 34 studies). We found that multimodality fusion models outperformed traditional single-modality models for the same task. Disease diagnosis and prediction were the most common clinical outcomes (reported in 20 and 10 studies, respectively) from a clinical outcome perspective.

Combating COVID-19 using Generative Adversarial Networks and Artificial Intelligence for Medical Images: A Scoping Review

This review presents a comprehensive study on the role of GANs in addressing the challenges related to COVID-19 data scarcity and diagnosis. It is the first review that summarizes the different GANs methods and the lungs images datasets for COVID-19. It attempts to answer the questions related to applications of GANs, popular GAN architectures, frequently used image modalities, and the availability of source code. This review included 57 full-text studies that reported the use of GANs for different applications in COVID-19 lungs images data. Most of the studies (n=42) used GANs for data augmentation to enhance the performance of AI techniques for COVID-19 diagnosis. Other popular applications of GANs were segmentation of lungs and super-resolution of the lungs images. The cycleGAN and the conditional GAN were the most commonly used architectures used in nine studies each. 29 studies used chest X-Ray images while 21 studies used CT images for the training of GANs. For majority of the studies (n=47), the experiments were done and results were reported using publicly available data. A secondary evaluation of the results by radiologists/clinicians was reported by only two studies. Conclusion: Studies have shown that GANs have great potential to address the data scarcity challenge for lungs images of COVID-19. Data synthesized with GANs have been helpful to improve the training of the Convolutional Neural Network (CNN) models trained for the diagnosis of COVID-19. Besides, GANs have also contributed to enhancing the CNNs performance through the super-resolution of the images and segmentation. This review also identified key limitations of the potential transformation of GANs based methods in clinical applications.

Modelling spatiotemporal variation of positive and negative sentiment on Twitter to improve the identification of localised deviations

Studies examining how sentiment on social media varies over time and space appear to produce inconsistent results. Analysing 16.54 million English-language tweets from 100 cities posted between 13 July and 30 November 2017, our aim was to clarify how spatiotemporal and social factors contributed to variation in sentiment on Twitter. We estimated positive and negative sentiment for each of the cities using dictionary-based sentiment analysis and constructed models to explain differences in sentiment using time of day, day of week, weather, interaction type (social or non-social), and city as factors. Tests in a distinct but contiguous period of time showed that all factors were independently associated with sentiment. In the full multivariable model of positive (Pearson's R in test data 0.236; 95% CI 0.231-0.241), and negative (Pearson's R in test data 0.306 95% CI 0.301-0.310) sentiment, city and time of day explained more of the variance than other factors. Extreme differences between observed and expected sentiment using the full model appeared to be better aligned with international news events than degenerate models. In applications that aim to detect localised events using the sentiment of Twitter populations, it is useful to account for baseline differences before looking for unexpected changes.