Communicating Smartly in the Molecular Domain: Neural Networks in the Internet of Bio-Nano Things

Recent developments in the Internet of Bio-Nano Things (IoBNT) are laying the groundwork for innovative applications across the healthcare sector. Nanodevices designed to operate within the body, managed remotely via the internet, are envisioned to promptly detect and actuate on potential diseases. In this vision, an inherent challenge arises due to the limited capabilities of individual nanosensors; specifically, nanosensors must communicate with one another to collaborate as a cluster. Aiming to research the boundaries of the clustering capabilities, this survey emphasizes data-driven communication strategies in molecular communication (MC) channels as a means of linking nanosensors. Relying on the flexibility and robustness of machine learning (ML) methods to tackle the dynamic nature of MC channels, the MC research community frequently refers to neural network (NN) architectures. This interdisciplinary research field encompasses various aspects, including the use of NNs to facilitate communication in MC environments, their implementation at the nanoscale, explainable approaches for NNs, and dataset generation for training. Within this survey, we provide a comprehensive analysis of fundamental perspectives on recent trends in NN architectures for MC, the feasibility of their implementation at the nanoscale, applied explainable artificial intelligence (XAI) techniques, and the accessibility of datasets along with best practices for their generation. Additionally, we offer open-source code repositories that illustrate NN-based methods to support reproducible research for key MC scenarios. Finally, we identify emerging research challenges, such as robust NN architectures, biologically integrated NN modules, and scalable training strategies.

Analysis and Compensation of Carrier Frequency Offset Impairments in Unique Word OFDM

Unique Word-orthogonal frequency division multiplexing (UW-OFDM) is known to provide various performance benefits over conventional cyclic prefix (CP) based OFDM. Most important, UW-OFDM features excellent spectral sidelobe suppression properties and an outstanding bit error ratio (BER) performance. Carrier frequency offset (CFO) induced impairments denote a challenging task for OFDM systems of any kind. In this work we investigate the CFO effects on UW-OFDM and compare it to conventional multi-carrier and single-carrier systems. Different CFO compensation approaches with different computational complexity are considered throughout this work and assessed against each other. A mean squared error analysis carried out after data estimation reveals a significant higher robustness of UW-OFDM over CP-OFDM against CFO effects. Additionally, the conducted BER simulations generally support this conclusion for various scenarios, ranging from uncoded to coded transmission in a frequency selective environment.