Freezing of Gait Prediction using Proactive Agent that Learns from Selected Experience and DDQN Algorithm

Freezing of Gait (FOG) is a debilitating motor symptom commonly experienced by individuals with Parkinson's Disease (PD) which often leads to falls and reduced mobility. Timely and accurate prediction of FOG episodes is essential for enabling proactive interventions through assistive technologies. This study presents a reinforcement learning-based framework designed to identify optimal pre-FOG onset points, thereby extending the prediction horizon for anticipatory cueing systems. The model implements a Double Deep Q-Network (DDQN) architecture enhanced with Prioritized Experience Replay (PER) allowing the agent to focus learning on high-impact experiences and refine its policy. Trained over 9000 episodes with a reward shaping strategy that promotes cautious decision-making, the agent demonstrated robust performance in both subject-dependent and subject-independent evaluations. The model achieved a prediction horizon of up to 8.72 seconds prior to FOG onset in subject-independent scenarios and 7.89 seconds in subject-dependent settings. These results highlight the model's potential for integration into wearable assistive devices, offering timely and personalized interventions to mitigate FOG in PD patients.

A Study on Simultaneous Use of a Robotic Walker and a Pneumatic Walking Assist Device Designed for PD Patients

Parkinson's disease (PD) is a common neurodegenerative disease that affects motor and non-motor symptoms. Postural instability and freezing of gait (FOG) are considered motor symptoms of PD resulting in falling. In this study, we investigated the effect of simultaneous use of a robotic walker and a pneumatic walking assist device (PWAD) for PD patients on gait features. The pneumatic actuated artificial muscle on the leg and actuators on the walker produce mutual induced stimulation, allowing the user to suppress FOG and maintain a stable gait pattern while walking. The performance of the proposed system was evaluated by conducting an 8 [m] straight-line walking task by a healthy subject with (a) RW (robotic walker), (b) simultaneous use of an RW and a PWAD, and some gait features for each condition were analyzed. The increasing stride length and decreasing stance phase duration in the gait cycle suggest that simultaneous use of a robotic walker and a pneumatic walking assist device would effectively decrease FOG and maintain a stable gait pattern for PD patients.