Predicting the meal macronutrient composition from continuous glucose monitors

Sustained high levels of blood glucose in type 2 diabetes (T2DM) can have disastrous long-term health consequences. An essential component of clinical interventions for T2DM is monitoring dietary intake to keep plasma glucose levels within an acceptable range. Yet, current techniques to monitor food intake are time intensive and error prone. To address this issue, we are developing techniques to automatically monitor food intake and the composition of those foods using continuous glucose monitors (CGMs). This article presents the results of a clinical study in which participants consumed nine standardized meals with known macronutrients amounts (carbohydrate, protein, and fat) while wearing a CGM. We built a multitask neural network to estimate the macronutrient composition from the CGM signal, and compared it against a baseline linear regression. The best prediction result comes from our proposed neural network, trained with subject-dependent data, as measured by root mean squared relative error and correlation coefficient. These findings suggest that it is possible to estimate macronutrient composition from CGM signals, opening the possibility to develop automatic techniques to track food intake.

Font Identification in Historical Documents Using Active Learning

Identifying the type of font (e.g., Roman, Blackletter) used in historical documents can help optical character recognition (OCR) systems produce more accurate text transcriptions. Towards this end, we present an active-learning strategy that can significantly reduce the number of labeled samples needed to train a font classifier. Our approach extracts image-based features that exploit geometric differences between fonts at the word level, and combines them into a bag-of-word representation for each page in a document. We evaluate six sampling strategies based on uncertainty, dissimilarity and diversity criteria, and test them on a database containing over 3,000 historical documents with Blackletter, Roman and Mixed fonts. Our results show that a combination of uncertainty and diversity achieves the highest predictive accuracy (89% of test cases correctly classified) while requiring only a small fraction of the data (17%) to be labeled. We discuss the implications of this result for mass digitization projects of historical documents.