Shifting to Machine Supervision: Annotation-Efficient Semi and Self-Supervised Learning for Automatic Medical Image Segmentation and Classification

Advancements in clinical treatment and research are limited by supervised learning techniques that rely on large amounts of annotated data, an expensive task requiring many hours of clinical specialists' time. In this paper, we propose using self-supervised and semi-supervised learning. These techniques perform an auxiliary task that is label-free, scaling up machine-supervision is easier compared with fully-supervised techniques. This paper proposes S4MI (Self-Supervision and Semi-Supervision for Medical Imaging), our pipeline to leverage advances in self and semi-supervision learning. We benchmark them on three medical imaging datasets to analyze their efficacy for classification and segmentation. This advancement in self-supervised learning with 10% annotation performed better than 100% annotation for the classification of most datasets. The semi-supervised approach yielded favorable outcomes for segmentation, outperforming the fully-supervised approach by using 50% fewer labels in all three datasets.

Enhancing Medical Image Segmentation: Optimizing Cross-Entropy Weights and Post-Processing with Autoencoders

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is heightened in medical image segmentation due to the high degree of inter-class similarities, intra-class variations, and possible image obfuscation. The segmentation task further diversifies when considering the study of histopathology slides for autoimmune diseases like dermatomyositis. The analysis of cell inflammation and interaction in these cases has been less studied due to constraints in data acquisition pipelines. Despite the progressive strides in medical science, we lack a comprehensive collection of autoimmune diseases. As autoimmune diseases globally escalate in prevalence and exhibit associations with COVID-19, their study becomes increasingly essential. While there is existing research that integrates artificial intelligence in the analysis of various autoimmune diseases, the exploration of dermatomyositis remains relatively underrepresented. In this paper, we present a deep-learning approach tailored for Medical image segmentation. Our proposed method outperforms the current state-of-the-art techniques by an average of 12.26% for U-Net and 12.04% for U-Net++ across the ResNet family of encoders on the dermatomyositis dataset. Furthermore, we probe the importance of optimizing loss function weights and benchmark our methodology on three challenging medical image segmentation tasks