Artefact-Aware Fungal Detection in Dermatophytosis: A Real-Time Transformer-Based Approach for KOH Microscopy

Dermatophytosis is commonly assessed using potassium hydroxide (KOH) microscopy, yet accurate recognition of fungal hyphae is hindered by artefacts, heterogeneous keratin clearance, and notable inter-observer variability. This study presents a transformer-based detection framework using the RT-DETR model architecture to achieve precise, query-driven localization of fungal structures in high-resolution KOH images. A dataset of 2,540 routinely acquired microscopy images was manually annotated using a multi-class strategy to explicitly distinguish fungal elements from confounding artefacts. The model was trained with morphology-preserving augmentations to maintain the structural integrity of thin hyphae. Evaluation on an independent test set demonstrated robust object-level performance, with a recall of 0.9737, precision of 0.8043, and an AP@0.50 of 93.56%. When aggregated for image-level diagnosis, the model achieved 100% sensitivity and 98.8% accuracy, correctly identifying all positive cases without missing a single diagnosis. Qualitative outputs confirmed the robust localization of low-contrast hyphae even in artefact-rich fields. These results highlight that an artificial intelligence (AI) system can serve as a highly reliable, automated screening tool, effectively bridging the gap between image-level analysis and clinical decision-making in dermatomycology.

Super-Resolution for Interferometric Imaging: Model Comparisons and Performance Analysis

This study investigates the application of Super-Resolution techniques in holographic microscopy to enhance quantitative phase imaging. An off-axis Mach-Zehnder interferometric setup was employed to capture interferograms. The study evaluates two Super-Resolution models, RCAN and Real-ESRGAN, for their effectiveness in reconstructing high-resolution interferograms from a microparticle-based dataset. The models were assessed using two primary approaches: image-based analysis for structural detail enhancement and morphological evaluation for maintaining sample integrity and phase map accuracy. The results demonstrate that RCAN achieves superior numerical precision, making it ideal for applications requiring highly accurate phase map reconstruction, while Real-ESRGAN enhances visual quality and structural coherence, making it suitable for visualization-focused applications. This study highlights the potential of Super-Resolution models in overcoming diffraction-imposed resolution limitations in holographic microscopy, opening the way for improved imaging techniques in biomedical diagnostics, materials science, and other high-precision fields.

CNN Based Detection of Cardiovascular Diseases from ECG Images

This study develops a Convolutional Neural Network (CNN) model for detecting myocardial infarction (MI) from Electrocardiogram (ECG) images. The model, built using the InceptionV3 architecture and optimized through transfer learning, was trained using ECG data obtained from the Ch. Pervaiz Elahi Institute of Cardiology in Pakistan. The dataset includes ECG images representing four different cardiac conditions: myocardial infarction, abnormal heartbeat, history of myocardial infarction, and normal heart activity. The developed model successfully detects MI and other cardiovascular conditions with an accuracy of 93.27%. This study demonstrates that deep learning-based models can provide significant support to clinicians in the early detection and prevention of heart attacks.