Automatic Extraction of Protein Interaction in Literature

Protein-protein interaction extraction is the key precondition of the construction of protein knowledge network, and it is very important for the research in the biomedicine. This paper extracted directional protein-protein interaction from the biological text, using the SVM-based method. Experiments were evaluated on the LLL05 corpus with good results. The results show that dependency features are import for the protein-protein interaction extraction and features related to the interaction word are effective for the interaction direction judgment. At last, we analyzed the effects of different features and planed for the next step.

Neural Mechanism of Language

This paper is based on our previous work on neural coding. It is a self-organized model supported by existing evidences. Firstly, we briefly introduce this model in this paper, and then we explain the neural mechanism of language and reasoning with it. Moreover, we find that the position of an area determines its importance. Specifically, language relevant areas are in the capital position of the cortical kingdom. Therefore they are closely related with autonomous consciousness and working memories. In essence, language is a miniature of the real world. Briefly, this paper would like to bridge the gap between molecule mechanism of neurons and advanced functions such as language and reasoning.

Motor Learning Mechanism on the Neuron Scale

Based on existing data, we wish to put forward a biological model of motor system on the neuron scale. Then we indicate its implications in statistics and learning. Specifically, neuron firing frequency and synaptic strength are probability estimates in essence. And the lateral inhibition also has statistical implications. From the standpoint of learning, dendritic competition through retrograde messengers is the foundation of conditional reflex and grandmother cell coding. And they are the kernel mechanisms of motor learning and sensory motor integration respectively. Finally, we compare motor system with sensory system. In short, we would like to bridge the gap between molecule evidences and computational models.

A Quantitative Neural Coding Model of Sensory Memory

The coding mechanism of sensory memory on the neuron scale is one of the most important questions in neuroscience. We have put forward a quantitative neural network model, which is self organized, self similar, and self adaptive, just like an ecosystem following Darwin theory. According to this model, neural coding is a mult to one mapping from objects to neurons. And the whole cerebrum is a real-time statistical Turing Machine, with powerful representing and learning ability. This model can reconcile some important disputations, such as: temporal coding versus rate based coding, grandmother cell versus population coding, and decay theory versus interference theory. And it has also provided explanations for some key questions such as memory consolidation, episodic memory, consciousness, and sentiment. Philosophical significance is indicated at last.

A Unified Quantitative Model of Vision and Audition

We have put forwards a unified quantitative framework of vision and audition, based on existing data and theories. According to this model, the retina is a feedforward network self-adaptive to inputs in a specific period. After fully grown, cells become specialized detectors based on statistics of stimulus history. This model has provided explanations for perception mechanisms of colour, shape, depth and motion. Moreover, based on this ground we have put forwards a bold conjecture that single ear can detect sound direction. This is complementary to existing theories and has provided better explanations for sound localization.