Medical imaging has revolutionized disease diagnosis, yet the potential is hampered by limited access to diverse and privacy-conscious datasets. Open-source medical datasets, while valuable, suffer from data quality and clinical information disparities. Generative models, such as diffusion models, aim to mitigate these challenges. At Stanford, researchers explored the utility of a fine-tuned Stable Diffusion model (RoentGen) for medical imaging data augmentation. Our work examines specific considerations to expand the Stanford research question, Could Stable Diffusion Solve a Gap in Medical Imaging Data? from the lens of bias and validity of the generated outcomes. We leveraged RoentGen to produce synthetic Chest-XRay (CXR) images and conducted assessments on bias, validity, and hallucinations. Diagnostic accuracy was evaluated by a disease classifier, while a COVID classifier uncovered latent hallucinations. The bias analysis unveiled disparities in classification performance among various subgroups, with a pronounced impact on the Female Hispanic subgroup. Furthermore, incorporating race and gender into input prompts exacerbated fairness issues in the generated images. The quality of synthetic images exhibited variability, particularly in certain disease classes, where there was more significant uncertainty compared to the original images. Additionally, we observed latent hallucinations, with approximately 42% of the images incorrectly indicating COVID, hinting at the presence of hallucinatory elements. These identifications provide new research directions towards interpretability of synthetic CXR images, for further understanding of associated risks and patient safety in medical applications.
A significant number of machine learning models are vulnerable to model extraction attacks, which focus on stealing the models by using specially curated queries against the target model. This task is well accomplished by using part of the training data or a surrogate dataset to train a new model that mimics a target model in a white-box environment. In pragmatic situations, however, the target models are trained on private datasets that are inaccessible to the adversary. The data-free model extraction technique replaces this problem when it comes to using queries artificially curated by a generator similar to that used in Generative Adversarial Nets. We propose for the first time, to the best of our knowledge, an adversary black box attack extending to a regression problem for predicting bounding box coordinates in object detection. As part of our study, we found that defining a loss function and using a novel generator setup is one of the key aspects in extracting the target model. We find that the proposed model extraction method achieves significant results by using reasonable queries. The discovery of this object detection vulnerability will support future prospects for securing such models.
Real-world deep learning models developed for Time Series Forecasting are used in several critical applications ranging from medical devices to the security domain. Many previous works have shown how deep learning models are prone to adversarial attacks and studied their vulnerabilities. However, the vulnerabilities of time series models for forecasting due to adversarial inputs are not extensively explored. While the attack on a forecasting model might aim to deteriorate the performance of the model, it is more effective, if the attack is focused on a specific impact on the model's output. In this paper, we propose a novel formulation of Directional, Amplitudinal, and Temporal targeted adversarial attacks on time series forecasting models. These targeted attacks create a specific impact on the amplitude and direction of the output prediction. We use the existing adversarial attack techniques from the computer vision domain and adapt them for time series. Additionally, we propose a modified version of the Auto Projected Gradient Descent attack for targeted attacks. We examine the impact of the proposed targeted attacks versus untargeted attacks. We use KS-Tests to statistically demonstrate the impact of the attack. Our experimental results show how targeted attacks on time series models are viable and are more powerful in terms of statistical similarity. It is, hence difficult to detect through statistical methods. We believe that this work opens a new paradigm in the time series forecasting domain and represents an important consideration for developing better defenses.