Physically-Constrained Harmonic Separation for Robust Heart and Respiratory Rate Estimation from Wrist Photoplethysmography

Wrist-worn photoplethysmography (PPG) enables continuous monitoring of cardiopulmonary physiology, but reliable heart rate (HR) and respiratory rate (RR) estimation in free-living conditions remains challenging due to non-stationary motion artifacts that spectrally overlap with physiological dynamics. Existing signal-processing methods degrade under strong motion, while unconstrained deep learning approaches often lack physiological interpretability and identifiable structure. We propose a Physically-Constrained Harmonic Separation (PCHS) framework that formulates HR and RR estimation from wrist PPG as an analysis-by-synthesis problem, where accelerometer measurements condition artifact separation rather than directly regressing vital signs. A physics-guided harmonic generator decomposes the observed signal into quasi-periodic physiological components and a motion-related residual, enabling HR recovery from the fundamental frequency and RR prediction from respiratory-driven modulations of the harmonic parameters. Robust reconstruction objectives, separation constraints, and uncertainty-aware weighting stabilize the decomposition under motion. Experiments on the motion-intensive PPG-DaLiA dataset demonstrate that PCHS outperforms state-of-the-art methods while yielding interpretable signal decompositions that effectively disentangle physiological activity from motion artifacts.

Improving Deep Learning-based Respiratory Sound Analysis with Frequency Selection and Attention Mechanism

Accurate classification of respiratory sounds requires deep learning models that effectively capture fine-grained acoustic features and long-range temporal dependencies. Convolutional Neural Networks (CNNs) are well-suited for extracting local time-frequency patterns but are limited in modeling global context. In contrast, transformer-based models can capture long-range dependencies, albeit with higher computational demands. To address these limitations, we propose a compact CNN-Temporal Self-Attention (CNN-TSA) network that integrates lightweight self-attention into an efficient CNN backbone. Central to our approach is a Frequency Band Selection (FBS) module that suppresses noisy and non-informative frequency regions, substantially improving accuracy and reducing FLOPs by up to 50%. We also introduce age-specific models to enhance robustness across diverse patient groups. Evaluated on the SPRSound-2022/2023 and ICBHI-2017 lung sound datasets, CNN-TSA with FBS sets new benchmarks on SPRSound and achieves state-of-the-art performance on ICBHI, all with a significantly smaller computational footprint. Furthermore, integrating FBS into an existing transformer baseline yields a new record on ICBHI, confirming FBS as an effective drop-in enhancement. These results demonstrate that our framework enables reliable, real-time respiratory sound analysis suitable for deployment in resource-constrained settings.