MIAdapt: Source-free Few-shot Domain Adaptive Object Detection for Microscopic Images

Existing generic unsupervised domain adaptation approaches require access to both a large labeled source dataset and a sufficient unlabeled target dataset during adaptation. However, collecting a large dataset, even if unlabeled, is a challenging and expensive endeavor, especially in medical imaging. In addition, constraints such as privacy issues can result in cases where source data is unavailable. Taking in consideration these challenges, we propose MIAdapt, an adaptive approach for Microscopic Imagery Adaptation as a solution for Source-free Few-shot Domain Adaptive Object detection (SF-FSDA). We also define two competitive baselines (1) Faster-FreeShot and (2) MT-FreeShot. Extensive experiments on the challenging M5-Malaria and Raabin-WBC datasets validate the effectiveness of MIAdapt. Without using any image from the source domain MIAdapt surpasses state-of-the-art source-free UDA (SF-UDA) methods by +21.3% mAP and few-shot domain adaptation (FSDA) approaches by +4.7% mAP on Raabin-WBC. Our code and models will be publicly available.

Few-Shot Domain Adaptive Object Detection for Microscopic Images

In recent years, numerous domain adaptive strategies have been proposed to help deep learning models overcome the challenges posed by domain shift. However, even unsupervised domain adaptive strategies still require a large amount of target data. Medical imaging datasets are often characterized by class imbalance and scarcity of labeled and unlabeled data. Few-shot domain adaptive object detection (FSDAOD) addresses the challenge of adapting object detectors to target domains with limited labeled data. Existing works struggle with randomly selected target domain images that may not accurately represent the real population, resulting in overfitting to small validation sets and poor generalization to larger test sets. Medical datasets exhibit high class imbalance and background similarity, leading to increased false positives and lower mean Average Precision (map) in target domains. To overcome these challenges, we propose a novel FSDAOD strategy for microscopic imaging. Our contributions include a domain adaptive class balancing strategy for few-shot scenarios, multi-layer instance-level inter and intra-domain alignment to enhance similarity between class instances regardless of domain, and an instance-level classification loss applied in the middle layers of the object detector to enforce feature retention necessary for correct classification across domains. Extensive experimental results with competitive baselines demonstrate the effectiveness of our approach, achieving state-of-the-art results on two public microscopic datasets. Code available at https://github.co/intelligentMachinesLab/few-shot-domain-adaptive-microscopy