A generalizable foundation model for intraoperative understanding across surgical procedures

In minimally invasive surgery, clinical decisions depend on real-time visual interpretation, yet intraoperative perception varies substantially across surgeons and procedures. This variability limits consistent assessment, training, and the development of reliable artificial intelligence systems, as most surgical AI models are designed for narrowly defined tasks and do not generalize across procedures or institutions. Here we introduce ZEN, a generalizable foundation model for intraoperative surgical video understanding trained on more than 4 million frames from over 21 procedures using a self-supervised multi-teacher distillation framework. We curated a large and diverse dataset and systematically evaluated multiple representation learning strategies within a unified benchmark. Across 20 downstream tasks and full fine-tuning, frozen-backbone, few-shot and zero-shot settings, ZEN consistently outperforms existing surgical foundation models and demonstrates robust cross-procedure generalization. These results suggest a step toward unified representations for surgical scene understanding and support future applications in intraoperative assistance and surgical training assessment.

CurConMix+: A Unified Spatio-Temporal Framework for Hierarchical Surgical Workflow Understanding

Surgical action triplet recognition aims to understand fine-grained surgical behaviors by modeling the interactions among instruments, actions, and anatomical targets. Despite its clinical importance for workflow analysis and skill assessment, progress has been hindered by severe class imbalance, subtle visual variations, and the semantic interdependence among triplet components. Existing approaches often address only a subset of these challenges rather than tackling them jointly, which limits their ability to form a holistic understanding. This study builds upon CurConMix, a spatial representation framework. At its core, a curriculum-guided contrastive learning strategy learns discriminative and progressively correlated features, further enhanced by structured hard-pair sampling and feature-level mixup. Its temporal extension, CurConMix+, integrates a Multi-Resolution Temporal Transformer (MRTT) that achieves robust, context-aware understanding by adaptively fusing multi-scale temporal features and dynamically balancing spatio-temporal cues. Furthermore, we introduce LLS48, a new, hierarchically annotated benchmark for complex laparoscopic left lateral sectionectomy, providing step-, task-, and action-level annotations. Extensive experiments on CholecT45 and LLS48 demonstrate that CurConMix+ not only outperforms state-of-the-art approaches in triplet recognition, but also exhibits strong cross-level generalization, as its fine-grained features effectively transfer to higher-level phase and step recognition tasks. Together, the framework and dataset provide a unified foundation for hierarchy-aware, reproducible, and interpretable surgical workflow understanding. The code and dataset will be publicly released on GitHub to facilitate reproducibility and further research.

AURA: Development and Validation of an Augmented Unplanned Removal Alert System using Synthetic ICU Videos

Unplanned extubation (UE) remains a critical patient safety concern in intensive care units (ICUs), often leading to severe complications or death. Real-time UE detection has been limited, largely due to the ethical and privacy challenges of obtaining annotated ICU video data. We propose Augmented Unplanned Removal Alert (AURA), a vision-based risk detection system developed and validated entirely on a fully synthetic video dataset. By leveraging text-to-video diffusion, we generated diverse and clinically realistic ICU scenarios capturing a range of patient behaviors and care contexts. The system applies pose estimation to identify two high-risk movement patterns: collision, defined as hand entry into spatial zones near airway tubes, and agitation, quantified by the velocity of tracked anatomical keypoints. Expert assessments confirmed the realism of the synthetic data, and performance evaluations showed high accuracy for collision detection and moderate performance for agitation recognition. This work demonstrates a novel pathway for developing privacy-preserving, reproducible patient safety monitoring systems with potential for deployment in intensive care settings.