Non-linear mechanical field reconstruction coupling recurrent neural networks with physics-informed graph neural networks

Reconstructing local stress fields in heterogeneous microstructures under non-linear, history-dependent loading remains a major computational bottleneck in multi-scale simulations. We propose a coupled LSTM-GNN framework that links the temporal and spatial aspects of local stress field reconstruction. A Long Short-Term Memory network encodes macroscopic stress-strain sequences into a compact hidden state that captures the path-dependent constitutive response, while a physics-informed Graph Neural Network reconstructs the spatially-resolved stress field at each time step. We introduce a relative weighting strategy with linear warm-up to balance the data-driven reconstruction loss and a discrete divergence-based equilibrium penalty. This resolves the scale mismatch that prevents fixed-weight formulations from converging in the elasto-plastic regime. The model is trained on 10,000 non-proportional loading paths applied to a periodic plate-with-a-hole microstructure and von Mises elasto-plasticity. The model achieves three orders of magnitude speedup over finite element simulations and generalizes to loading sequences twice the training length, with 1.9% cumulative error. Because the graph relies on mesh connectivity instead of the specific element type, one trained surrogate can be applied directly without retraining to meshes with different element types and to both coarser and finer resolutions, while in all cases reproducing the high-fidelity quad-element FE field used during training. Indeed, the message passing characteristics inherent to GNN and MeshGraphNet architecture render the model mesh-agnostic. Analysis of the LSTM hidden states suggests a low-dimensional structure related to the internal state variables of the constitutive model.

Toward Semantic-Agnostic and Shape-Aware Vision-Language Segmentation Models

Vision-language segmentation models have recently achieved strong performance by leveraging high-level semantic object categories expressed in natural language. However, this semantic dependence limits their ability to reason about intrinsic visual properties such as shape, geometry, or texture, which are essential in many real-world applications. In this work, we introduce Semantic-Agnostic aNd Shape-Aware (SANSA) segmentation, a new paradigm that requires segmentation models to operate solely from non-semantic textual descriptions. To this end, we propose two strategies to generate SANSA segmentation prompts based on either dictionary constraints or example guidance, both generating semantic-agnostic textual descriptions. These prompts are then used to finetune segmentation models under semantic-agnostic supervision. Experiments show that finetuning on SANSA prompts yields up to a 20% mIoU improvement on this new segmentation task, compared to pretrained state-of-the-art models, while maintaining strong performance on standard semantic prompts. These results highlight the importance of low- and mid-level visual reasoning for improving the generalization and controllability of vision-language segmentation models.

H-SPAM: Hierarchical Superpixel Anything Model

Superpixels offer a compact image representation by grouping pixels into coherent regions. Recent methods have reached a plateau in terms of segmentation accuracy by generating noisy superpixel shapes. Moreover, most existing approaches produce a single fixed-scale partition that limits their use in vision pipelines that would benefit multi-scale representations. In this work, we introduce H-SPAM (Hierarchical Superpixel Anything Model), a unified framework for generating accurate, regular, and perfectly nested hierarchical superpixels. Starting from a fine partition, guided by deep features and external object priors, H-SPAM constructs the hierarchy through a two-phase region merging process that first preserves object consistency and then allows controlled inter-object grouping. The hierarchy can also be modulated using visual attention maps or user input to preserve important regions longer in the hierarchy. Experiments on standard benchmarks show that H-SPAM strongly outperforms existing hierarchical methods in both accuracy and regularity, while performing on par with most recent state-of-the-art non-hierarchical methods. Code and pretrained models are available: https://github.com/waldo-j/hspam.

Superpixel Anything: A general object-based framework for accurate yet regular superpixel segmentation

Superpixels are widely used in computer vision to simplify image representation and reduce computational complexity. While traditional methods rely on low-level features, deep learning-based approaches leverage high-level features but also tend to sacrifice regularity of superpixels to capture complex objects, leading to accurate but less interpretable segmentations. In this work, we introduce SPAM (SuperPixel Anything Model), a versatile framework for segmenting images into accurate yet regular superpixels. We train a model to extract image features for superpixel generation, and at inference, we leverage a large-scale pretrained model for semantic-agnostic segmentation to ensure that superpixels align with object masks. SPAM can handle any prior high-level segmentation, resolving uncertainty regions, and is able to interactively focus on specific objects. Comprehensive experiments demonstrate that SPAM qualitatively and quantitatively outperforms state-of-the-art methods on segmentation tasks, making it a valuable and robust tool for various applications. Code and pre-trained models are available here: https://github.com/waldo-j/spam.

Superpixel Segmentation: A Long-Lasting Ill-Posed Problem

For many years, image over-segmentation into superpixels has been essential to computer vision pipelines, by creating homogeneous and identifiable regions of similar sizes. Such constrained segmentation problem would require a clear definition and specific evaluation criteria. However, the validation framework for superpixel methods, typically viewed as standard object segmentation, has rarely been thoroughly studied. In this work, we first take a step back to show that superpixel segmentation is fundamentally an ill-posed problem, due to the implicit regularity constraint on the shape and size of superpixels. We also demonstrate through a novel comprehensive study that the literature suffers from only evaluating certain aspects, sometimes incorrectly and with inappropriate metrics. Concurrently, recent deep learning-based superpixel methods mainly focus on the object segmentation task at the expense of regularity. In this ill-posed context, we show that we can achieve competitive results using a recent architecture like the Segment Anything Model (SAM), without dedicated training for the superpixel segmentation task. This leads to rethinking superpixel segmentation and the necessary properties depending on the targeted downstream task.

Deep Spherical Superpixels

Over the years, the use of superpixel segmentation has become very popular in various applications, serving as a preprocessing step to reduce data size by adapting to the content of the image, regardless of its semantic content. While the superpixel segmentation of standard planar images, captured with a 90{\deg} field of view, has been extensively studied, there has been limited focus on dedicated methods to omnidirectional or spherical images, captured with a 360{\deg} field of view. In this study, we introduce the first deep learning-based superpixel segmentation approach tailored for omnidirectional images called DSS (for Deep Spherical Superpixels). Our methodology leverages on spherical CNN architectures and the differentiable K-means clustering paradigm for superpixels, to generate superpixels that follow the spherical geometry. Additionally, we propose to use data augmentation techniques specifically designed for 360{\deg} images, enabling our model to efficiently learn from a limited set of annotated omnidirectional data. Our extensive validation across two datasets demonstrates that taking into account the inherent circular geometry of such images into our framework improves the segmentation performance over traditional and deep learning-based superpixel methods. Our code is available online.

3D Transformer based on deformable patch location for differential diagnosis between Alzheimer's disease and Frontotemporal dementia

Alzheimer's disease and Frontotemporal dementia are common types of neurodegenerative disorders that present overlapping clinical symptoms, making their differential diagnosis very challenging. Numerous efforts have been done for the diagnosis of each disease but the problem of multi-class differential diagnosis has not been actively explored. In recent years, transformer-based models have demonstrated remarkable success in various computer vision tasks. However, their use in disease diagnostic is uncommon due to the limited amount of 3D medical data given the large size of such models. In this paper, we present a novel 3D transformer-based architecture using a deformable patch location module to improve the differential diagnosis of Alzheimer's disease and Frontotemporal dementia. Moreover, to overcome the problem of data scarcity, we propose an efficient combination of various data augmentation techniques, adapted for training transformer-based models on 3D structural magnetic resonance imaging data. Finally, we propose to combine our transformer-based model with a traditional machine learning model using brain structure volumes to better exploit the available data. Our experiments demonstrate the effectiveness of the proposed approach, showing competitive results compared to state-of-the-art methods. Moreover, the deformable patch locations can be visualized, revealing the most relevant brain regions used to establish the diagnosis of each disease.

Brain Structure Ages -- A new biomarker for multi-disease classification

Age is an important variable to describe the expected brain's anatomy status across the normal aging trajectory. The deviation from that normative aging trajectory may provide some insights into neurological diseases. In neuroimaging, predicted brain age is widely used to analyze different diseases. However, using only the brain age gap information (\ie the difference between the chronological age and the estimated age) can be not enough informative for disease classification problems. In this paper, we propose to extend the notion of global brain age by estimating brain structure ages using structural magnetic resonance imaging. To this end, an ensemble of deep learning models is first used to estimate a 3D aging map (\ie voxel-wise age estimation). Then, a 3D segmentation mask is used to obtain the final brain structure ages. This biomarker can be used in several situations. First, it enables to accurately estimate the brain age for the purpose of anomaly detection at the population level. In this situation, our approach outperforms several state-of-the-art methods. Second, brain structure ages can be used to compute the deviation from the normal aging process of each brain structure. This feature can be used in a multi-disease classification task for an accurate differential diagnosis at the subject level. Finally, the brain structure age deviations of individuals can be visualized, providing some insights about brain abnormality and helping clinicians in real medical contexts.

Deep Grading based on Collective Artificial Intelligence for AD Diagnosis and Prognosis

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two tasks using structural MRI. However, these methods often suffer from lack of interpretability, generalization, and can be limited in terms of performance. In this paper, we propose a novel deep framework designed to overcome these limitations. Our framework consists of two stages. In the first stage, we propose a deep grading model to extract meaningful features. To enhance the robustness of these features against domain shift, we introduce an innovative collective artificial intelligence strategy for training and evaluating steps. In the second stage, we use a graph convolutional neural network to better capture AD signatures. Our experiments based on 2074 subjects show the competitive performance of our deep framework compared to state-of-the-art methods on different datasets for both AD diagnosis and prognosis.

Deep grading for MRI-based differential diagnosis of Alzheimer's disease and Frontotemporal dementia

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is sometimes difficult for physicians. Therefore, an accurate tool dedicated to this diagnostic challenge can be valuable in clinical practice. However, current structural imaging methods mainly focus on the detection of each disease but rarely on their differential diagnosis. In this paper, we propose a deep learning based approach for both problems of disease detection and differential diagnosis. We suggest utilizing two types of biomarkers for this application: structure grading and structure atrophy. First, we propose to train a large ensemble of 3D U-Nets to locally determine the anatomical patterns of healthy people, patients with Alzheimer's disease and patients with Frontotemporal dementia using structural MRI as input. The output of the ensemble is a 2-channel disease's coordinate map able to be transformed into a 3D grading map which is easy to interpret for clinicians. This 2-channel map is coupled with a multi-layer perceptron classifier for different classification tasks. Second, we propose to combine our deep learning framework with a traditional machine learning strategy based on volume to improve the model discriminative capacity and robustness. After both cross-validation and external validation, our experiments based on 3319 MRI demonstrated competitive results of our method compared to the state-of-the-art methods for both disease detection and differential diagnosis.