i6mA-CNN: a convolution based computational approach towards identification of DNA N6-methyladenine sites in rice genome

DNA N6-methylation (6mA) in Adenine nucleotide is a post replication modification and is responsible for many biological functions. Experimental methods for genome wide 6mA site detection is an expensive and manual labour intensive process. Automated and accurate computational methods can help to identify 6mA sites in long genomes saving significant time and money. Our study develops a convolutional neural network based tool i6mA-CNN capable of identifying 6mA sites in the rice genome. Our model coordinates among multiple types of features such as PseAAC inspired customized feature vector, multiple one hot representations and dinucleotide physicochemical properties. It achieves area under the receiver operating characteristic curve of 0.98 with an overall accuracy of 0.94 using 5 fold cross validation on benchmark dataset. Finally, we evaluate our model on two other plant genome 6mA site identification datasets besides rice. Results suggest that our proposed tool is able to generalize its ability of 6mA site identification on plant genomes irrespective of plant species. Web tool for this research can be found at: https://cutt.ly/Co6KuWG. Supplementary data (benchmark dataset, independent test dataset, comparison purpose dataset, trained model, physicochemical property values, attention mechanism details for motif finding) are available at https://cutt.ly/PpDdeDH.

Automatic Signboard Detection from Natural Scene Image in Context of Bangladesh Google Street View

Automatic signboard region detection is the first step of information extraction about establishments from an image, especially when there is a complex background and multiple signboard regions are present in the image. Automatic signboard detection in Bangladesh is a challenging task because of low quality street view image, presence of overlapping objects and presence of signboard like objects which are not actually signboards. In this research, we provide a novel dataset from the perspective of Bangladesh city streets with an aim of signboard detection, namely Bangladesh Street View Signboard Objects (BSVSO) image dataset. We introduce a novel approach to detect signboard accurately by applying smart image processing techniques and statistically determined hyperparameter based deep learning method, Faster R-CNN. Comparison of different variations of this segmentation based learning method have also been performed in this research.