Development and Validation of SXI++ LNM Algorithm for Sepsis Prediction

Sepsis is a life-threatening condition affecting over 48.9 million people globally and causing 11 million deaths annually. Despite medical advancements, predicting sepsis remains a challenge due to non-specific symptoms and complex pathophysiology. The SXI++ LNM is a machine learning scoring system that refines sepsis prediction by leveraging multiple algorithms and deep neural networks. This study aims to improve robustness in clinical applications and evaluates the predictive performance of the SXI++ LNM for sepsis prediction. The model, utilizing a deep neural network, was trained and tested using multiple scenarios with different dataset distributions. The model's performance was assessed against unseen test data, and accuracy, precision, and area under the curve (AUC) were calculated. THE SXI++ LNM outperformed the state of the art in three use cases, achieving an AUC of 0.99 (95% CI: 0.98-1.00). The model demonstrated a precision of 99.9% (95% CI: 99.8-100.0) and an accuracy of 99.99% (95% CI: 99.98-100.0), maintaining high reliability.

Generalizability and Application of the Skin Reflectance Estimate Based on Dichromatic Separation (SREDS)

Face recognition (FR) systems have become widely used and readily available in recent history. However, differential performance between certain demographics has been identified within popular FR models. Skin tone differences between demographics can be one of the factors contributing to the differential performance observed in face recognition models. Skin tone metrics provide an alternative to self-reported race labels when such labels are lacking or completely not available e.g. large-scale face recognition datasets. In this work, we provide a further analysis of the generalizability of the Skin Reflectance Estimate based on Dichromatic Separation (SREDS) against other skin tone metrics and provide a use case for substituting race labels for SREDS scores in a privacy-preserving learning solution. Our findings suggest that SREDS consistently creates a skin tone metric with lower variability within each subject and SREDS values can be utilized as an alternative to the self-reported race labels at minimal drop in performance. Finally, we provide a publicly available and open-source implementation of SREDS to help the research community. Available at https://github.com/JosephDrahos/SREDS

Data-Driven Nonlinear TDOA for Accurate Source Localization in Complex Signal Dynamics

The complex and dynamic propagation of oscillations and waves is often triggered by sources at unknown locations. Accurate source localization enables the elimination of the rotor core in atrial fibrillation (AFib) as an effective treatment for such severe cardiac disorder; it also finds potential use in locating the spreading source in natural disasters such as forest fires and tsunamis. However, existing approaches such as time of arrival (TOA) and time difference of arrival (TDOA) do not yield accurate localization results since they tacitly assume a constant signal propagation speed whereas realistic propagation is often non-static and heterogeneous. In this paper, we develop a nonlinear TDOA (NTDOA) approach which utilizes observational data from various positions to jointly learn the propagation speed at different angles and distances as well as the location of the source itself. Through examples of simulating the complex dynamics of electrical signals along the surface of the heart and satellite imagery from forest fires and tsunamis, we show that with a small handful of measurements, NTDOA, as a data-driven approach, can successfully locate the spreading source, leading also to better forecasting of the speed and direction of subsequent propagation.

A novel non-linear transformation based multi-user identification algorithm for fixed text keystroke behavioral dynamics

In this paper, we propose a new technique to uniquely classify and identify multiple users accessing a single application using keystroke dynamics. This problem is usually encountered when multiple users have legitimate access to shared computers and accounts, where, at times, one user can inadvertently be logged in on another user's account. Since the login processes are usually bypassed at this stage, we rely on keystroke dynamics in order to tell users apart. Our algorithm uses the quantile transform and techniques from localization to classify and identify users. Specifically, we use an algorithm known as ordinal Unfolding based Localization (UNLOC), which uses only ordinal data obtained from comparing distance proxies, by "locating" users in a reduced PCA/Kernel-PCA/t-SNE space based on their typing patterns. Our results are validated with the help of benchmark keystroke datasets and show that our algorithm outperforms other methods.

SREDS: A dichromatic separation based measure of skin color

Face recognition (FR) systems are fast becoming ubiquitous. However, differential performance among certain demographics was identified in several widely used FR models. The skin tone of the subject is an important factor in addressing the differential performance. Previous work has used modeling methods to propose skin tone measures of subjects across different illuminations or utilized subjective labels of skin color and demographic information. However, such models heavily rely on consistent background and lighting for calibration, or utilize labeled datasets, which are time-consuming to generate or are unavailable. In this work, we have developed a novel and data-driven skin color measure capable of accurately representing subjects' skin tone from a single image, without requiring a consistent background or illumination. Our measure leverages the dichromatic reflection model in RGB space to decompose skin patches into diffuse and specular bases.