Bonsai: A Framework for Convolutional Neural Network Acceleration Using Criterion-Based Pruning

As the need for more accurate and powerful Convolutional Neural Networks (CNNs) increases, so too does the size, execution time, memory footprint, and power consumption. To overcome this, solutions such as pruning have been proposed with their own metrics and methodologies, or criteria, for how weights should be removed. These solutions do not share a common implementation and are difficult to implement and compare. In this work, we introduce Combine, a criterion- based pruning solution and demonstrate that it is fast and effective framework for iterative pruning, demonstrate that criterion have differing effects on different models, create a standard language for comparing criterion functions, and propose a few novel criterion functions. We show the capacity of these criterion functions and the framework on VGG inspired models, pruning up to 79\% of filters while retaining or improving accuracy, and reducing the computations needed by the network by up to 68\%.

Guide-Guard: Off-Target Predicting in CRISPR Applications

With the introduction of cyber-physical genome sequencing and editing technologies, such as CRISPR, researchers can more easily access tools to investigate and create remedies for a variety of topics in genetics and health science (e.g. agriculture and medicine). As the field advances and grows, new concerns present themselves in the ability to predict the off-target behavior. In this work, we explore the underlying biological and chemical model from a data driven perspective. Additionally, we present a machine learning based solution named \textit{Guide-Guard} to predict the behavior of the system given a gRNA in the CRISPR gene-editing process with 84\% accuracy. This solution is able to be trained on multiple different genes at the same time while retaining accuracy.