Augment to Augment: Diverse Augmentations Enable Competitive Ultra-Low-Field MRI Enhancement

Ultra-low-field (ULF) MRI promises broader accessibility but suffers from low signal-to-noise ratio (SNR), reduced spatial resolution, and contrasts that deviate from high-field standards. Image-to-image translation can map ULF images to a high-field appearance, yet efficacy is limited by scarce paired training data. Working within the ULF-EnC challenge constraints (50 paired 3D volumes; no external data), we study how task-adapted data augmentations impact a standard deep model for ULF image enhancement. We show that strong, diverse augmentations, including auxiliary tasks on high-field data, substantially improve fidelity. Our submission ranked third by brain-masked SSIM on the public validation leaderboard and fourth by the official score on the final test leaderboard. Code is available at https://github.com/fzimmermann89/low-field-enhancement.

PINQI: An End-to-End Physics-Informed Approach to Learned Quantitative MRI Reconstruction

Quantitative Magnetic Resonance Imaging (qMRI) enables the reproducible measurement of biophysical parameters in tissue. The challenge lies in solving a nonlinear, ill-posed inverse problem to obtain the desired tissue parameter maps from acquired raw data. While various learned and non-learned approaches have been proposed, the existing learned methods fail to fully exploit the prior knowledge about the underlying MR physics, i.e. the signal model and the acquisition model. In this paper, we propose PINQI, a novel qMRI reconstruction method that integrates the knowledge about the signal, acquisition model, and learned regularization into a single end-to-end trainable neural network. Our approach is based on unrolled alternating optimization, utilizing differentiable optimization blocks to solve inner linear and non-linear optimization tasks, as well as convolutional layers for regularization of the intermediate qualitative images and parameter maps. This design enables PINQI to leverage the advantages of both the signal model and learned regularization. We evaluate the performance of our proposed network by comparing it with recently published approaches in the context of highly undersampled $T_1$-mapping, using both a simulated brain dataset, as well as real scanner data acquired from a physical phantom and in-vivo data from healthy volunteers. The results demonstrate the superiority of our proposed solution over existing methods and highlight the effectiveness of our method in real-world scenarios.