Securing Genomic Data Against Inference Attacks in Federated Learning Environments

Federated Learning (FL) offers a promising framework for collaboratively training machine learning models across decentralized genomic datasets without direct data sharing. While this approach preserves data locality, it remains susceptible to sophisticated inference attacks that can compromise individual privacy. In this study, we simulate a federated learning setup using synthetic genomic data and assess its vulnerability to three key attack vectors: Membership Inference Attack (MIA), Gradient-Based Membership Inference Attack, and Label Inference Attack (LIA). Our experiments reveal that Gradient-Based MIA achieves the highest effectiveness, with a precision of 0.79 and F1-score of 0.87, underscoring the risk posed by gradient exposure in federated updates. Additionally, we visualize comparative attack performance through radar plots and quantify model leakage across clients. The findings emphasize the inadequacy of na\"ive FL setups in safeguarding genomic privacy and motivate the development of more robust privacy-preserving mechanisms tailored to the unique sensitivity of genomic data.

Red Teaming the Mind of the Machine: A Systematic Evaluation of Prompt Injection and Jailbreak Vulnerabilities in LLMs

Large Language Models (LLMs) are increasingly integrated into consumer and enterprise applications. Despite their capabilities, they remain susceptible to adversarial attacks such as prompt injection and jailbreaks that override alignment safeguards. This paper provides a systematic investigation of jailbreak strategies against various state-of-the-art LLMs. We categorize over 1,400 adversarial prompts, analyze their success against GPT-4, Claude 2, Mistral 7B, and Vicuna, and examine their generalizability and construction logic. We further propose layered mitigation strategies and recommend a hybrid red-teaming and sandboxing approach for robust LLM security.