Topic Diffusion Discovery Based on Deep Non-negative Autoencoder

Researchers have been overwhelmed by the explosion of research articles published by various research communities. Many research scholarly websites, search engines, and digital libraries have been created to help researchers identify potential research topics and keep up with recent progress on research of interests. However, it is still difficult for researchers to keep track of the research topic diffusion and evolution without spending a large amount of time reviewing numerous relevant and irrelevant articles. In this paper, we consider a novel topic diffusion discovery technique. Specifically, we propose using a Deep Non-negative Autoencoder with information divergence measurement that monitors evolutionary distance of the topic diffusion to understand how research topics change with time. The experimental results show that the proposed approach is able to identify the evolution of research topics as well as to discover topic diffusions in online fashions.

Discovering Drug-Drug and Drug-Disease Interactions Inducing Acute Kidney Injury Using Deep Rule Forests

Patients with Acute Kidney Injury (AKI) increase mortality, morbidity, and long-term adverse events. Therefore, early identification of AKI may improve renal function recovery, decrease comorbidities, and further improve patients' survival. To control certain risk factors and develop targeted prevention strategies are important to reduce the risk of AKI. Drug-drug interactions and drug-disease interactions are critical issues for AKI. Typical statistical approaches cannot handle the complexity of drug-drug and drug-disease interactions. In this paper, we propose a novel learning algorithm, Deep Rule Forests (DRF), which discovers rules from multilayer tree models as the combinations of drug usages and disease indications to help identify such interactions. We found that several disease and drug usages are considered having significant impact on the occurrence of AKI. Our experimental results also show that the DRF model performs comparatively better than typical tree-based and other state-of-the-art algorithms in terms of prediction accuracy and model interpretability.

Towards Interpretable Deep Extreme Multi-label Learning

Many Machine Learning algorithms, such as deep neural networks, have long been criticized for being "black-boxes"-a kind of models unable to provide how it arrive at a decision without further efforts to interpret. This problem has raised concerns on model applications' trust, safety, nondiscrimination, and other ethical issues. In this paper, we discuss the machine learning interpretability of a real-world application, eXtreme Multi-label Learning (XML), which involves learning models from annotated data with many pre-defined labels. We propose a two-step XML approach that combines deep non-negative autoencoder with other multi-label classifiers to tackle different data applications with a large number of labels. Our experimental result shows that the proposed approach is able to cope with many-label problems as well as to provide interpretable label hierarchies and dependencies that helps us understand how the model recognizes the existences of objects in an image.